Results 41 to 50 of about 338,965 (297)

Integrated Metabolomic and Transcriptomic Analysis of Phenylpropanoid Biosynthesis in Silphium perfoliatum

Current Issues in Molecular Biology
Silphium perfoliatum is a promising economic plant rich in bioactive secondary metabolites, yet the molecular regulation of phenylpropanoid biosynthesis across development remains unclear.
Guoying Zhang, Dejun Zhang
doaj   +1 more source

Development and Validation of the Whole Atmosphere Community Climate Model With Thermosphere and Ionosphere Extension (WACCM‐X 2.0)

Journal of Advances in Modeling Earth Systems, 2018
Key developments have been made to the NCAR Whole Atmosphere Community Climate Model with thermosphere and ionosphere extension (WACCM‐X). Among them, the most important are the self‐consistent solution of global electrodynamics, and transport of O+ in ...
Han‐Li Liu, Charles G. Bardeen, Benjamin T. Foster, Peter Lauritzen, Jing Liu, Gang Lu, Daniel R. Marsh, Astrid Maute, Joseph M. McInerney, Nicholas M. Pedatella, Liying Qian, Arthur D. Richmond, Raymond G. Roble, Stanley C. Solomon, Francis M. Vitt, Wenbin Wang   +15 more
doaj   +1 more source

An improved formula for standard hypoxia tolerance time (STT) to evaluate hypoxic tolerance in mice

Military Medical Research, 2018
Background Hypoxia is a primary cause of mountain sickness and a common pathological condition in patients with heart failure, shock, stroke, and chronic obstructive pulmonary disease (COPD).
Gang Xu, Yu-Qi Gao, Yi-Xing Gao, Gang Wu, Jian-Yang Zhang, Wen-Xiang Gao   +5 more
doaj   +1 more source

Hydrochemical and quality assessment of irrigation water at the trans-himalayan high-altitude regions of Leh, Ladakh, India

Applied Water Science, 2022
A total of seventy irrigation water samples were collected from Leh, Ladakh, India, to determine their hydrochemistry profile and water quality for irrigation purposes.
Arup Giri, Vijay K. Bharti, Sahil Kalia, Krishna Kumar, Mayarngam Khansu   +4 more
doaj   +1 more source

Integrated pan-cancer analysis and experimental verification of the roles of tropomyosin 4 in gastric cancer

Frontiers in Immunology, 2023
ObjectiveTo investigate the function of tropomyosin 4 (TPM4) using pan-cancer data, especially in gastric cancer (GC), using comprehensive bioinformatics analysis and molecular experiments.MethodsWe used UCSC Xena, The Cancer Genome Atlas (TCGA ...
Qijing Guo, Qijing Guo, Linglin Zhao, Nan Yan, Yan Li, Cuiping Guo, Shengyan Dang, Xianliang Shen, Jianfang Han, Yushuang Luo, Yushuang Luo   +10 more
doaj   +1 more source

Urbanization and altitude are associated with low kidney function in Peru [PDF]

, 2019
Background: Kidney health needs to be studied in low- and middle-income countries with populations living at high altitude and undergoing urbanization. We studied whether greater level of urbanization was associated with worse kidney function; and higher
Narvaez-Guerra, Offdan, Smeeth, Liam, Carrillo Larco, Rodrigo, Miranda, J Jaime, Bernabe-Ortiz, Antonio, CRONICAS Cohort Study Group, Herrera-Enriquez, Karela, Checkley, William, Gilman, Robert H, Carrillo-Larco, Rodrigo M, Medina-Lezama, Josefina   +10 more
core   +1 more source

Multiobjective Codesign Optimization of a Planar Pneumatic Artificial Muscle‐Based Snake‐Like Robot for Enhanced Agility and Energy Efficiency

Advanced Robotics Research, EarlyView.
A codesign multiobjective optimization framework was developed to enhance the morphology and controller of a snake‐like robot driven by artificial muscles. It improved planar locomotion, agility, and power efficiency. The approach optimized link geometry and controller gains, revealing that shorter muscles near joints and longer linkages maximize ...
Ayla Valles, Mahdi Haghshenas‐Jaryani
wiley   +1 more source

Activation of notch signaling pathway is a potential mechanism for mucin2 reduction and intestinal mucosal barrier dysfunction in high-altitude hypoxia

Scientific Reports
High-altitude hypoxia can cause gastrointestinal issues and damage the intestinal mucosal barrier, which is crucial for digestion and nutrient absorption. The Notch signaling pathway affects this barrier’s integrity. This study explores the Notch pathway’
Ruhan Jia, Ying Han, Qinfang Zhu, Jingxuan Zhang, Huan Zhang, Maojia Ka, Yi Ma, Mohammed Gamah, Wei Zhang   +8 more
doaj   +1 more source

Memory impairment induced by exposure to simulated hypobaric hypoxia and phosphoproteomic analysis of hippocampus in mice

Di-san junyi daxue xuebao, 2022
Objective To observe the changes of protein phosphorylation levels in the hippocampus of mice with memory impairment caused by hypobaric hypoxia exposure, and to explore the key phosphorylated proteins and associated pathways involved in memory deficits.
DONG Huaping, ZHONG Zhifeng, LI Peng, HUANG Pei, TIAN Huaijun, XIE Jiaxin, ZHOU Simin   +6 more
doaj   +1 more source

Altitude Hypoxia Increases Glucose Uptake in Human Heart [PDF]

, 2010
[[abstract]]Chen, Chi-Hsien, Yuh-Feng Liu, Shin-Da Lee, Wen-Chih Lee, Ying-Lan Tsai, Chien-Wen Hou, Chih-Yang Huang, and Chia-Hua Kuo. Altitude hypoxia increases glucose uptake in human heart. High Alt. Med Biol.
Chen, CH (Chen, Chi-Hsien); Liu, YF (Liu, Yuh-Feng); Lee, SD (Lee, Shin-Da); Huang, CY (Huang, Chih-Yang); Lee, WC (Lee, Wen-Chih); Tsai, YL (Tsai, Ying-Lan); Hou, CW (Hou, Chien-Wen); Chan, YS (Chan, Yi-Sheng); Kuo, CH (Kuo, Chia-Hua)
core