Results 51 to 60 of about 350,286 (305)

Integrated Metabolomic and Transcriptomic Analysis of Phenylpropanoid Biosynthesis in Silphium perfoliatum

open access: yesCurrent Issues in Molecular Biology
Silphium perfoliatum is a promising economic plant rich in bioactive secondary metabolites, yet the molecular regulation of phenylpropanoid biosynthesis across development remains unclear.
Guoying Zhang, Dejun Zhang
doaj   +1 more source

Development and Validation of the Whole Atmosphere Community Climate Model With Thermosphere and Ionosphere Extension (WACCM‐X 2.0)

open access: yesJournal of Advances in Modeling Earth Systems, 2018
Key developments have been made to the NCAR Whole Atmosphere Community Climate Model with thermosphere and ionosphere extension (WACCM‐X). Among them, the most important are the self‐consistent solution of global electrodynamics, and transport of O+ in ...
Han‐Li Liu   +15 more
doaj   +1 more source

An improved formula for standard hypoxia tolerance time (STT) to evaluate hypoxic tolerance in mice

open access: yesMilitary Medical Research, 2018
Background Hypoxia is a primary cause of mountain sickness and a common pathological condition in patients with heart failure, shock, stroke, and chronic obstructive pulmonary disease (COPD).
Gang Xu   +5 more
doaj   +1 more source

Integrated pan-cancer analysis and experimental verification of the roles of tropomyosin 4 in gastric cancer

open access: yesFrontiers in Immunology, 2023
ObjectiveTo investigate the function of tropomyosin 4 (TPM4) using pan-cancer data, especially in gastric cancer (GC), using comprehensive bioinformatics analysis and molecular experiments.MethodsWe used UCSC Xena, The Cancer Genome Atlas (TCGA ...
Qijing Guo   +10 more
doaj   +1 more source

Altitude Hypoxia Increases Glucose Uptake in Human Heart [PDF]

open access: yes, 2010
[[abstract]]Chen, Chi-Hsien, Yuh-Feng Liu, Shin-Da Lee, Wen-Chih Lee, Ying-Lan Tsai, Chien-Wen Hou, Chih-Yang Huang, and Chia-Hua Kuo. Altitude hypoxia increases glucose uptake in human heart. High Alt. Med Biol.
Chen, CH (Chen, Chi-Hsien); Liu, YF (Liu, Yuh-Feng); Lee, SD (Lee, Shin-Da); Huang, CY (Huang, Chih-Yang); Lee, WC (Lee, Wen-Chih); Tsai, YL (Tsai, Ying-Lan); Hou, CW (Hou, Chien-Wen); Chan, YS (Chan, Yi-Sheng); Kuo, CH (Kuo, Chia-Hua)
core  

Origami‐Inspired Morphing Fuselage for Agile Fixed‐Wing Flight

open access: yesAdvanced Robotics Research, EarlyView.
Conventional aircraft steer with rigid control surfaces. SoAR instead replaces the fuselage itself with a cable‐driven origami continuum body that bends in 3D and compresses on demand. Whole‐fuselage morphing steers fixed‐wing flight: achieving sharp, near‐zero‐radius turns and rapid braking without ailerons, rudder, or elevator, while the same ...
Abudula Aihaitijiang, Cagdas D. Onal
wiley   +1 more source

Activation of notch signaling pathway is a potential mechanism for mucin2 reduction and intestinal mucosal barrier dysfunction in high-altitude hypoxia

open access: yesScientific Reports
High-altitude hypoxia can cause gastrointestinal issues and damage the intestinal mucosal barrier, which is crucial for digestion and nutrient absorption. The Notch signaling pathway affects this barrier’s integrity. This study explores the Notch pathway’
Ruhan Jia   +8 more
doaj   +1 more source

Hydrochemical and quality assessment of irrigation water at the trans-himalayan high-altitude regions of Leh, Ladakh, India

open access: yesApplied Water Science, 2022
A total of seventy irrigation water samples were collected from Leh, Ladakh, India, to determine their hydrochemistry profile and water quality for irrigation purposes.
Arup Giri   +4 more
doaj   +1 more source

Memory impairment induced by exposure to simulated hypobaric hypoxia and phosphoproteomic analysis of hippocampus in mice

open access: yesDi-san junyi daxue xuebao, 2022
Objective To observe the changes of protein phosphorylation levels in the hippocampus of mice with memory impairment caused by hypobaric hypoxia exposure, and to explore the key phosphorylated proteins and associated pathways involved in memory deficits.
DONG Huaping   +6 more
doaj   +1 more source

Nanometer Layer Coating to Lactose Particles for Optimization of Dexamethasone Pulmonary Delivery

open access: yesAdvanced Science, EarlyView.
Nanometer layer coating (NLC) was investigated and its mechanism illustrated by advanced characterization techniques. The effects and application for the inhalation of dexamethasone (DEX) were demonstrated through in vitro and in vivo evaluation. This approach increased DEX bioavailability and enabled the dose to be reduced to 1/30 of the intravenous ...
Qin Nie   +11 more
wiley   +1 more source

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