Results 71 to 80 of about 338,965 (297)

Red Blood Cells as Endogenous Biotweezers for Optical Micromanipulation In Vivo

Advanced Science, EarlyView.
By synergistically integrating the long‐distance manipulation fiber probe (LDMFP) and endogenous red blood cells (RBCs) as biocompatible optical elements, a natural RBC biotweezer was developed for the desired microparticle manipulation and immune cell activation within living vasculature, which might offer an alternative tool for intravital optical ...
Tong Yang, Xinyu Ren, Dalin Ma, Hao Pang, Wei Chen, Kaize Cai, Mei Yuan, Bingzhi Zhang, Zufang Lin, Xiaoshuai Liu   +9 more
wiley   +1 more source

Hypoxic preacclimatization combining intermittent hypoxia exposure with physical exercise significantly promotes the tolerance to acute hypoxia

Frontiers in Physiology
Background: Both hypoxia exposure and physical exercise before ascending have been proved to promote high altitude acclimatization, whether the combination of these two methods can bring about a better effect remains uncertain.
Jiaxin Xie, Shenwei Xie, Zhifeng Zhong, Huaping Dong, Pei Huang, Simin Zhou, Huaijun Tian, Jijian Zhang, Yu Wu, Peng Li   +9 more
doaj   +1 more source

Hypoxia Exacerbates Inflammatory Acute Lung Injury via the Toll-Like Receptor 4 Signaling Pathway

Frontiers in Immunology, 2018
Acute lung injury (ALI) is characterized by non-cardiogenic diffuse alveolar damage and often leads to a lethal consequence, particularly when hypoxia coexists.
Gang Wu, Gang Wu, Gang Xu, Gang Xu, De-Wei Chen, De-Wei Chen, Wen-Xiang Gao, Wen-Xiang Gao, Jian-Qiong Xiong, Hai-Ying Shen, Yu-Qi Gao, Yu-Qi Gao   +11 more
doaj   +1 more source

Nanometer Layer Coating to Lactose Particles for Optimization of Dexamethasone Pulmonary Delivery

Advanced Science, EarlyView.
Nanometer layer coating (NLC) was investigated and its mechanism illustrated by advanced characterization techniques. The effects and application for the inhalation of dexamethasone (DEX) were demonstrated through in vitro and in vivo evaluation. This approach increased DEX bioavailability and enabled the dose to be reduced to 1/30 of the intravenous ...
Qin Nie, Jiahe Liu, Xiangyu Zhao, Siying Yang, Han Sun, Bingqian Jia, Xiaohong Ren, Xintao Chen, Lixin Sun, Li Wu, Caifen Wang, Jiwen Zhang   +11 more
wiley   +1 more source

Groundwater Rise Sustains the World's Largest Alpine Water System Under Global Warming

Advanced Science, EarlyView.
Shallow groundwater depth (SGWD) across the non‐permafrost plains of the Qinghai–Xizang Plateau decreased at averagely 0.02 m year−1, adding 31.44 Gt of freshwater storage from 2000 to 2020 and sustaining ∼53 500 km2 of alpine ecosystems. A vadose‐zone capacity of 426.6 Gt reveals these aquifers as promising reservoirs, highlighting groundwater's ...
Jianqing Du, Zhixiang Niu, Yanfen Wang, Shirui Zhou, Youqing Yang, Xiang Wei, Haishan Niu, Yitao Zhang, Anquan Xia, Yali Liu, Yanbin Hao, Kai Xue, Bingfang Wu, Xinquan Zhao, Tandong Yao, Yiyu Chen   +15 more
wiley   +1 more source

Tumor cell-derived EMP1 is essential for cancer-associated fibroblast infiltration in tumor microenvironment of triple-negative breast cancer

Cell Death and Disease
The role of epithelial membrane protein 1 (EMP1) in tumor microenvironment (TME) remodeling has not yet been elucidated. In addition, the biological function of EMP1 in triple-negative breast cancer (TNBC) is largely unclear.
Qi Wang, Dandan Li, Haixiu Ma, Zengyan Li, Juan Wu, Jinwan Qiao, Jun Liu, Jing Zhao, Ronghua Ma, Lin Tian, Lei Zhang, Jianye Yang, Jianing Wang, Shanshan Qin, Zhanhai Su   +14 more
doaj   +1 more source

Adriamycin-induced podocyte injury via the Sema3A/TRPC5/Rac1 pathway

Frontiers in Medicine
Podocytopathies encompass kidney diseases where direct or indirect podocyte injury leads to proteinuria or nephrotic syndrome. Although Semaphorin3A (Sema3A) is expressed in podocytes and tubular cells in adult mammalian kidneys and has a common effect ...
Yan Liu, Yan Liu, Ri-Li Ge, Zhen-Zhen Shan, Yan-Jun Wang, Yan-Yan Yang, Xue Sun, Peng-Li Luo, Peng-Li Luo   +8 more
doaj   +1 more source

Effect of inhaled nitric oxide on oxygen-carrying capacity of red blood cells and hypoxia tolerance in mice

Di-san junyi daxue xuebao, 2019
Objective To study the effects of nitric oxide (NO) inhalation on oxygen-carrying capacity of red blood cells and hypoxia tolerance in mice. Methods Peripheral blood from 8-week-old male mice was exposed to nitrogen gas containing NO in an oxygenation ...
SU Wenting, CUI Yu, LI Xiaoxu, GUAN Libin   +3 more
doaj   +1 more source

China's Low‐Carbon Energy Transition Over the Past Two Decades: Experiences and Implications

Advanced Science, EarlyView.
China's low‐carbon energy transition features a brief decline and subsequent rebound in coal consumption, alongside the rapid expansion of renewable energy. This study develops a stage‐based analytical framework to explain this evolution from the perspectives of economic development, energy security, and environmental sustainability, revealing how ...
Yu Liu, Zhiyu Tian, Zhengxian Zhang, Xinbei Li   +3 more
wiley   +1 more source

Growth pattern of Saudi schoolboys in a high-altitude area of Saudi Arabia [PDF]

, 1995
205-209The aim of the present study was to examine the growth of schoolboys in a high-altitude area of Saudi Arabia, and to investigate the appropriateness of using the US National Center for Health Statistics [NCHS] standards for the assessment of ...
Abolfotouh, Mostafa A., Badawi, Ibrahim A.   +1 more
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