ALV-J-contaminated commercial live vaccines induced pathogenicity in Three-Yellow chickens: one of the transmission routes of ALV-J to commercial chickens. [PDF]
One avian leukosis virus of subgroup J (ALV-J) strain GX14YYA1 was isolated from a commercial bivalent Newcastle disease (ND)-infectious bronchitis (IB) vaccine in our previous study. To evaluate the pathogenicity of the ALV-J-contaminated vaccine on commercial chickens, day-old Three-Yellow chicks in group I were vaccinated with ALV-J-contaminated ...
Wang P +9 more
europepmc +6 more sources
LncIRF1 promotes chicken resistance to ALV-J infection. [PDF]
The pathogenesis of avian leukosis virus subgroup J (ALV-J) is complex and our understanding of it is limited. Based on our previous research, we explored the relationship between ALV-J infection and regulatory factor 1&7 (IRF1 and IRF7), interferon beta (IFNβ), and the newly identified long noncoding RNA IRF1 (LncIRF1).
Wang L +7 more
europepmc +3 more sources
Cholesterol-25-hydroxylase Is a Chicken ISG That Restricts ALV-J Infection by Producing 25-hydroxycholesterol [PDF]
The avian leukosis virus subgroup J (ALV-J) belongs to the chicken retrovirus that causes enormous economic losses in the poultry industry. Interferon-stimulated genes (ISGs) are critical for controlling virus infections.
Tingting Xie +7 more
doaj +2 more sources
Knockout of p53 leads to a significant increase in ALV-J replication. [PDF]
Avian leukemia is a common malignant disease, and and its regulatory mechanism is complex. As the most extensive tumor suppressor gene in cancer research, p53 can control multiple functions such as that of DNA repair, induction of apoptosis, cell cycle arrest and so on.
Zhang H +6 more
europepmc +4 more sources
Comparative analysis of the exosomal contents of DF-1 cells infected by ALV-J. [PDF]
Exploration of the abnormal expression of exosomal molecules during the infection of avian leukosis virus subgroup J (ALV-J) is essential to provide a deeper understanding of the exosome's role in the viral pathogenesis involved. The study aimed to investigate the differentially expressed proteins and miRNAs of the exosomes derived from DF-1 cells ...
Yang J, Zhuang P, Cheng Z, Wang G.
europepmc +5 more sources
Circ_PIAS1 Promotes the Apoptosis of ALV-J Infected DF1 Cells by Up-Regulating miR-183. [PDF]
(1) Background: circRNAs are closed circular molecules with covalent bonds generated by reverse shearing, which have high stability and have different manifestations in different tissues, cells, or physiological conditions and play important roles in various disease processes and physiological processes.
Yang T +8 more
europepmc +3 more sources
: Avian leukosis virus subgroup J (ALV-J) is an avian oncogenic retrovirus that has caused huge economic losses in the poultry industry due to its great pathogenicity and transmission ability.
Houkun Wang +9 more
doaj +1 more source
Avian leukosis (AL), caused by avian leukosis virus (ALV), is a contagious tumor disease that results in significant economic losses for the poultry industry.
Junfeng Dou +10 more
doaj +1 more source
Synergistic pathogenesis of chicken infectious anemia virus and J subgroup of avian leukosis virus
: As important immunosuppressive viruses, chicken infectious anemia virus (CIAV) and subgroup J avian leukosis virus (ALV-J) have caused huge economic losses to the poultry industry globally.
Jun Zhang +10 more
doaj +1 more source
Synergistic Pathogenicity of REV and ALV-J in Chicks by Vertical Transmission of Chicken Embryos
【Objective】Avian leukosis virus subgroup J (ALV-J) and reticuloendotheliosis virus (REV) can be transmitted vertically through chicken embryos, and there have been reports of chicken embryos that are co-infected with the two viruses, however, the ...
Lingyao MA +4 more
doaj +1 more source

