Results 61 to 70 of about 5,574 (141)

MicroRNA expression profile in extracellular vesicles derived from ALV-J infected chicken semen

Virus Research, 2020
MicroRNAs(miRNAs) have been reported to regulate gene expression in many processes. MiRNA in extracellular vesicles (EVs) also have been widely investigated, while there is no studies of miRNAs in seminal EVs. Subgroup J of Avian leukosis virus (ALV-J) can be transmitted vertically, but the mechanism of it is not clear enough. This study was to examine
Sheng, Chen, Liqin, Liao, Qiqi, Zhao, Xinheng, Zhang, Hongxin, Li, Wencheng, Lin, Feng, Chen, Qingmei, Xie   +7 more
openaire   +2 more sources

Identification of novel B-cell epitope in gp85 of subgroup J avian leukosis virus and its application in diagnosis of disease

BMC Veterinary Research, 2018
Background The gp85 is the main envelope protein of avian leukosis subgroup J (ALV-J) involved in virus neutralization. Here, we mapped the epitope in ALV-J gp85 by ELISA using synthetic peptides and developed epitope based diagnostic methods for ALV-J ...
Kun Qian, Xue Tian, Hongxia Shao, Jianqiang Ye, Yongxiu Yao, Venugopal Nair, Aijian Qin   +6 more
doaj   +1 more source

PERFECTA Loaded Lipid Cubosomes for 19F‐MRI: Physico‐Chemical Characterization

Chemistry – A European Journal, EarlyView.
Phytantriol‐based cubosomes loaded with PERFCTA, a fluorinated MRI probe, were developed as promising systems for imaging and drug delivery. The nanoparticles showed high PERFECTA encapsulation efficiency, strong fluorine MRI signals, and optimal colloidal stability in biological media.
Pietro Milesi, Beatrice Lucia Bona, Cristina Chirizzi, Marco Campanile, Pompea Del Vecchio, Marc Schmutz, Valerie Sartor, Debora Berti, Pierangelo Metrangolo, Francesca Baldelli Bombelli, Barbara Lonetti   +10 more
wiley   +1 more source

Immunopathological investigation and genetic evolution of Avian leukosis virus Subgroup-J associated with myelocytomatosis in broiler flocks in Egypt

Virology Journal
Background Avian leukosis virus Subgroup-J (ALV-J) is a rapidly oncogenic evolving retrovirus infecting a variety of avian species; causing severe economic losses to the local poultry industry.
Ahmed Fotouh, Eman Abd El-Menamm Shosha, Ali Mahmood Zanaty, Marwa Mostafa Darwesh   +3 more
doaj   +1 more source

Gut microbiota profiles of commercial laying hens infected with tumorigenic viruses

BMC Veterinary Research, 2020
Background Studies have shown that some viral infections cause structural changes in the intestinal microflora, but little is known about the effects of tumorigenic viral infection on the intestinal microflora of chickens.
Xianhua Wan, Laipeng Xu, Xiangli Sun, Hui Li, Fengbin Yan, Ruili Han, Hong Li, Zhuanjian Li, Yadong Tian, Xiaojun Liu, Xiangtao Kang, Zhenya Wang, Yanbin Wang   +12 more
doaj   +1 more source

Controllable DNA Condensation by Mixed Cationic Gemini/Nonionic Surfactant Systems: Structure, Thermodynamics, and Cytotoxicity

Journal of Surfactants and Detergents, EarlyView.
ABSTRACT Controllable DNA condensation is important for nucleic‐acid packaging and non‐viral gene‐delivery systems. This study aimed to determine how the composition of mixed nonionic C12E10 and cationic gemini C12C6C12Br2 surfactants regulates DNA condensation, structure, thermodynamics, and cytotoxicity.
Bo Wang, Linyi Zhu, Yaxun Fan, Yilin Wang   +3 more
wiley   +1 more source

Exosomal miR-7-25207 Increases Subgroup J Avian Leukosis Virus Titers by Targeting the Akt-CyclinQ1 and PRC1-YAF2 Dual Pathways

Microorganisms
Subgroup J avian leukosis virus (ALV-J) is a major pathogen in poultry, causing substantial economic losses to the poultry industry worldwide. Exosomal small RNAs derived from virus-infected cells or biological fluids can serve as viral transmission ...
Xiaona Zeng, Tongfei Liu, Shengqiu Tang, Xiaoying Dong, Yajuan Li, Liqin Liao, Sheng Chen, Liyi Chen, Jie Kong, Zhenkai Dai, Keyu Feng, Yung-Hou Wong, Qingmei Xie   +12 more
doaj   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, EarlyView.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source

Role of O-linked glycosylation modification on internalization and replication of avian leukosis virus subgroup J

Veterinary Research
Upon infection, viruses reprogram the host metabolic system to hijack metabolic resources for proliferation. Avian leukosis virus subgroup J (ALV-J), an avian oncogenic virus, poses significant challenges to the poultry industry. ALV-J infection upgrades
Moru Xu, Menglu Xu, He Zhu, Kun Qian, Hongxia Shao, Jinlin Huang, Jianqiang Ye, Aijian Qin   +7 more
doaj   +1 more source

A chicken liver cell line efficiently supports the replication of ALV-J possibly through its high level viral receptor and efficient protein expression system

Veterinary Research, 2018
In this study, we identified a chicken liver cell line (LMH) which could strongly support the replication of ALV-J (Subgroup J of avian leukosis virus) with high viral titer.
Tuofan Li, Jing Xie, Lu Lv, Shu Sun, Xiaomei Dong, Quan Xie, Guangcheng Liang, Chichao Xia, Hongxia Shao, Aijian Qin, Jianqiang Ye   +10 more
doaj   +1 more source