Results 81 to 90 of about 243,774 (341)

Incidence of bone loss in primary teeth: a retrospective analysis of contributing factors

Scientific Reports
Periodontitis affects not only adults but also children, targeting their primary teeth and leading to diagnostic challenges and future implications for their permanent teeth.
Sara Zissu, Uri Renert, Tal Ratson, Michael Saminsky, Omer Cohen, Gil Slutzkey, Maayan Gal, Eran Gabay, Evgeny Weinberg   +8 more
doaj   +1 more source

Sclerostin is essential for alveolar bone loss in occlusal hypofunction

Experimental and Therapeutic Medicine, 2016
Bone loss is caused by occlusal hypofunction and is a serious health concern. This is particularly true of tooth loss, which is common in the elderly. However, the cellular and molecular mechanisms underlying bone loss have yet to be fully elucidated.
Xuefeng Zhao, Tian Chen, Huan Zeng, Tian Gao, Ding Bai, Yang Xu, Yanmin Wang, Lufei Wang, Xin Xu, Yao Sun, Xianglong Han   +10 more
openaire   +4 more sources

Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model

Advanced Healthcare Materials, EarlyView.
A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark, Fereshteh Bayat, Sara Rahmani, Mathura Thirugnanasampanthar, Taylor Kramer, Elise Schwarz, David Wilson, Jeffrey I. Weitz, Zeinab Hosseinidoust, Tohid F. Didar   +9 more
wiley   +1 more source

The effect of colchicine on alveolar bone loss in ligature-induced periodontitis

Brazilian Oral Research, 2019
Colchicine is widely used in the treatment of several inflammatory diseases due to its anti-inflammatory effect, but effects on bone metabolism are unclear.
Hulya TOKER, Hatice BALCI YUCE, Ali YILDIRIM, Mehmet Buğrul TEKİN, Fikret GEVREK   +4 more
doaj   +1 more source

A Novel Core–Shell Hydrogel 3D Model for Studying Macrophage Mechanosensing and Foreign Body Giant Cell Formation

Advanced Healthcare Materials, EarlyView.
The foreign body response (FBR) to biomaterials is primarily driven by macrophages, which often fuse into destructive foreign body giant cells (FBGCs). To address the limited understanding of FBGC formation, a novel microscale core–shell hydrogel 3D model is developed using heterogeneous alginate‐collagen microcapsules with varying stiffness, offering ...
Manisha Mahanty, Wenquan Ou, Xiaoping Zhu, Jonathan S Bromberg, Xiaoming He, Shaik O. Rahaman   +5 more
wiley   +1 more source

Changes in alveolar bone support induced by the Herbst appliance: a tomographic evaluation

Dental Press Journal of Orthodontics, 2016
Objective: This study evaluated alveolar bone loss around mandibular incisors, induced by the Herbst appliance. Methods: The sample consisted of 23 patients (11 men, 12 women; mean age of 15.76 ± 1.75 years), Class II, Division 1 malocclusion, treated
João Paulo Schwartz, Taisa Boamorte Raveli, Humberto Osvaldo Schwartz-Filho, Dirceu Barnabé Raveli   +3 more
doaj   +1 more source

Treatment of OPG-deficient mice with WP9QY, a RANKL-binding peptide, recovers alveolar bone loss by suppressing osteoclastogenesis and enhancing osteoblastogenesis

PLoS ONE, 2017
Osteoblasts express two key molecules for osteoclast differentiation, receptor activator of NF-κB ligand (RANKL) and osteoprotegerin (OPG), a soluble decoy receptor for RANKL.
Yuki Ozaki, M. Koide, Y. Furuya, T. Ninomiya, H. Yasuda, Midori Nakamura, Yasuhiro Kobayashi, N. Takahashi, N. Yoshinari, N. Udagawa   +9 more
semanticscholar   +1 more source

Xeno‐Free Biocompatible Peptide‐Based Bioinks Reinforced with Cellulose Nanofibers for 3D Printing

Advanced Healthcare Materials, EarlyView.
A xeno‐free bioink combining self‐assembled peptides and cellulose nanofibers is developed for 3D printing. The bioink forms a non‐cross‐linked 3D scaffold, mimicking the extracellular matrix and supporting over 95% cell viability. This approach offers enhanced biocompatibility and mechanical stability, advancing 3D printing for personalized medicine ...
Francesca Netti, Mor Tsuriano, Noam Rattner, Vania Altobelli, Yoav Dan, Lihi Adler‐Abramovich   +5 more
wiley   +1 more source

Interleukin-33 and RANK-L Interplay in the Alveolar Bone Loss Associated to Periodontitis

PLoS ONE, 2016
Introduction Chronic Periodontitis (CP) is an inflammatory disease of bacterial origin that results in alveolar bone destruction. Porphyromonas gingivalis (Pg), one of the main periopathogens, initiates an inflammatory cascade by host immune cells ...
Olivier Lapérine, A. Cloitre, J. Caillon, O. Huck, I. Bugueno, P. Pilet, S. Sourice, E. Le Tilly, G. Palmer, J. Davideau, V. Geoffroy, J. Guicheux, S. Beck-Cormier, P. Lesclous   +13 more
semanticscholar   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun, Elizabeth S. Nakasone, Ha Eun Shin, Hyojin Lee, Jong‐Chan Park, Wonhwa Lee, Wooram Park, Chun Gwon Park, Juwon Park, Se‐Na Kim   +9 more
wiley   +1 more source