Abstract Rhodococcus equi is a facultative intracellular pathogen and a major cause of pneumonia in foals worldwide. The standard treatment for affected foals is a combination of a macrolide with rifampicin. The widespread use of this combination has led to the emergence of multidrug‐resistant (MDR) strains of R. equi.
Marlane Geribone Seeger +7 more
wiley +1 more source
Indole-acetaldehyde from Rothia mucilaginosa activates the PXR/NRF2 axis to enhance alveolar macrophage phagocytosis and protect against ARDS. [PDF]
Fan W +9 more
europepmc +1 more source
Targeting eEF1A1 with baicalein disrupts the eEF1A1‐Prdx4 interaction to prevent RNF14‐mediated ubiquitination and degradation of Prdx4. This stabilizes Prdx4 to suppress NF‐κB, thereby alleviating sepsis‐induced acute lung injury. ABSTRACT Sepsis is a systemic inflammatory response syndrome triggered by an uncontrolled host response to infection ...
Jing Chang +9 more
wiley +1 more source
Single-cell transcriptomics reveal alveolar macrophage-specific responses in single-hit ozone exposure model in mice. [PDF]
Vo T, Choudhary I, Patial S, Saini Y.
europepmc +1 more source
Untethered Electrical Stimulation Using Optoelectricity and Piezoelectricity for Tissue Regeneration
Untethered electrical stimulation from optoelectronic and piezoelectric materials can aid regeneration of damaged tissue. ABSTRACT Electrical signals are increasingly recognized as important regulators of tissue development and regeneration, with outcomes linked to behaviors including proliferation, differentiation, cell migration, and more.
Ryan Yao, Baochun Xu, Cunjiang Yu
wiley +1 more source
Comparative lobe-specific histomorphometric evaluation of pulmonary architecture, fibrosis, and alveolar macrophage distribution in swine raised under different management systems. [PDF]
Chaiyawong N +5 more
europepmc +1 more source
Mn<sup>2+</sup>-Mediated Antiviral Activity Through Both the cGAS-STING-IFN and ROS-Apoptosis Pathways in Porcine Alveolar Macrophage Cells. [PDF]
Zheng W +10 more
europepmc +1 more source
An alveolar macrophage-targeted ciprofloxacin polymeric prodrug improves survival in a murine model of <i>Klebsiella pneumoniae</i> pneumonia. [PDF]
López CL +14 more
europepmc +1 more source
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Sulforaphane Pre-Treatment Improves Alveolar Macrophage Killing After Alcohol-Induced Phagocytic Dysfunction In Vitro and in <i>Galleria mellonella</i> Larvae. [PDF]
Harrop C +10 more
europepmc +1 more source

