Results 181 to 190 of about 331,012 (291)

Mechanisms by which SIRT2 modulates alveolar macrophage immunoreactivity to intervene in Actinobacillus pleuropneumoniae infection in piglets under cold stimulation. [PDF]

Vet Res
Xia R, Xing W, Zhu Z, Han Q, Chen X, Shi H, Wu W, Zhang B, Lu J, Guo W, He L, Xu B.   +11 more
europepmc   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

BMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu, Renwang Sheng, Mumin Cao, Ludvig J. Backman, Yucheng Gao, Hao Wang, Cheng Zhang, Jialin Chen, Wei Zhang, Yunfeng Rui   +9 more
wiley   +1 more source

<i>Pseudomonas aeruginosa</i> infection is associated with alveolar macrophage M2 polarization via MERTK-mediated NLRC4 inflammasome activation. [PDF]

J Med Microbiol
Chen R, Xu Y.
europepmc   +1 more source

Caveolin‐1 enriched apoptotic bodies derived from oral hard palate orchestrate bone remodeling to treat heterotopic ossification

BMEMat, EarlyView.
Downregulated CAV1 in HO is restored via apoptotic bodies from PMSCs, which reprogram bone remodeling by delivering CAV1 to target cells, highlighting the therapeutic role of EV subtypes in heterotopic ossification. Abstract Heterotopic ossification (HO) is a pathological process characterized by ectopic bone formation in non‐osseous tissues, with an ...
Yuchen Wang, Like Tang, Zhou Yu, Wenjin Cai, Qifeng Jiang, Zhikang Wang, Yitong Chen, Kaichen Lai, Ying Wang, Tim Forouzanfar, Chiyuan Ma, Gang Wu, Tingben Huang, Guoli Yang   +13 more
wiley   +1 more source

LACC1 attenuates LPS-induced acute lung injury by inhibiting inflammatory response in alveolar macrophage through LPAR3/PI3K/AKT/mTOR signaling pathway. [PDF]

Biomark Res
He Y, Huang Y, Wang L, Hao S, Wang X, Han M, Zhou K, Xuan L, Ju M.   +8 more
europepmc   +1 more source

Glycopolymeric nanoparticles transported by activated platelets protect ischemic myocardium by alleviating PANoptosis through targeting macrophage Dectin‐1

BMEMat, EarlyView.
NP‐SF, designed to target macrophage Dectin‐1 and activated platelets, selectively accumulated in ischemic myocardium, where it was taken up by macrophages after platelet hitchhiking. By inhibiting NLRC5‐related PANoptosis, NP‐SF significantly attenuated pathological damage, and effectively preserved cardiac function in a murine ischemia–reperfusion ...
Guanye Yu, Na Yang, Yan Zhang, Lingxin Peng, Yi Li, Yue Chao, Qinfang Miao, Haikun Qi, Jianhui Zhuang, Weixia Jian, Bingyu Li, Wenhui Peng, Jinghua Chen, Shiyu Gong   +13 more
wiley   +1 more source

Human alveolar macrophage function is impaired in tuberculosis contacts with diabetes. [PDF]

EBioMedicine
Kleynhans L, Kunsevi-Kilola C, Tshivhula H, Webber T, Keyser A, Prins N, Snyders CI, Shabangu A, Rozot V, Kidd M, Zhang H, Cai H, Wang Y, Ewing AD, Malherbe ST, Azad AK, Arnett E, Restrepo BI, Schlesinger LS, Ronacher K.   +19 more
europepmc   +1 more source

Mechanism study of an articular cartilage repair material and its forward‐looking test for space medicine

BMEMat, EarlyView.
The regeneration process following dLhCG engraftment progressed through four distinct and interconnected stages. dLhCG maintained its regenerative efficacy after 6 months of cosmic exposure, supporting its potential application in space medicine.
Xu Hu, Hang Yao, Zhen Zhang, Zhonglian Wu, Huiqun Zhou, Bangheng Liu, Liang Ma, Yulei Mu, Dong‐An Wang   +8 more
wiley   +1 more source

RANKL promotes airway inflammation via pro-inflammatory alveolar macrophage activation in COPD. [PDF]

Respir Res
Zhou L, Zhang B, Wang H, Liu J, Miao L.
europepmc   +1 more source

Integrating chemo‐mechanical cues in nano‐microscale environments for stem cell regulation

BMEMat, EarlyView.
Nano/microscale control strategies, including nano/microscale materials, ligand spacings, and cell encapsulating gels, cell mechanics, integrin signaling, and biochemical cues to direct stem cell fate, tissue regeneration, and organoid engineering, enabling advanced biomedical applications through mechanoregulation at cell‐material interfaces ...
Rajendra K. Singh, Varsha Sagar, Amal George Kurian, Shreyas Kumar Jain, Hye Sung Kim, Hae‐Won Kim   +5 more
wiley   +1 more source