Results 161 to 170 of about 331,012 (291)

Ac‐SDKP modulates apoptosis via HSP27 and the FAS/FASL and mitochondrial axes

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of Ac‐SDKP regulating the FAS/FASL and mitochondrial apoptosis pathways via HSP27. Ac‐SDKP inhibits HSP27 expression, activates the FAS/FASL pathway and Caspase‐3 signaling, increases Caspase‐8 and Caspase‐3 expression, and induces cell apoptosis.
Wenxin Guo, Jinyin Yan, Wenli Li, Jin Wang, Lu Liu, Chengmei Zhang, Wei Cao, Shanshan Yao, Haibo Gong, Yi He, Zihan Zhou, Siyan Chen, Li Feng, Haijing Deng   +13 more
wiley   +1 more source

<i>Prevotella intermedia</i> culture supernatant impairs alveolar macrophage function and promotes <i>Mycobacterium avium</i> persistence. [PDF]

Virulence
Fukushima K, Iwanaga N, Takeda K, Hirayama T, Yoshida M, Ide S, Tashiro M, Takazono T, Kosai K, Sakamoto N, Izumikawa K, Naito M, Yanagihara K, Mukae H.   +13 more
europepmc   +1 more source

Marine‐Derived Type I Collagen From Scyliorhinus canicula: Extraction, Characterization, and Biomedical Applications

Journal of Applied Polymer Science, EarlyView.
Marine‐derived type I collagen is extracted from Scyliorhinus canicula skin and characterized by physicochemical and morphological analyses. The collagen exhibits excellent biocompatibility, promotes wound healing, reduces inflammatory mediators, and inhibits melanogenesis.
Marwa Rejeb, Aida Lahmar, Arem Selmi, Tahsine Kosksi, Nawres Debbabi, Ghania Hamdi‐Degobert, Leila Chekir‐Ghedira   +6 more
wiley   +1 more source

Alveolar macrophage subtypes express cholesterol and inflammation genes in cystic fibrosis. [PDF]

Life Sci Alliance
Li X, Kolling FW, Aridgides D, Gwilt L, Mellinger D, Jakubzick CV, Ashare A.   +6 more
europepmc   +1 more source

MiniSdd7‐Derived Cytosine Base Editor Promotes Efficient Multiplex Gene Knockout in Porcine Primary Fibroblasts

Animal Research and One Health, EarlyView.
The miniSdd7‐BE4max‐SpG system enables highly efficient multiplex C‐to‐T base editing of APN, CD163, and MSTN in porcine fibroblasts, providing a robust platform for future development of multiplex gene‐edited livestock. ABSTRACT Efficient multiplex genome editing is essential for improving complex traits in livestock that are governed by multiple ...
Shaoshuai Wang, Yu Wang, Dengfeng Bi, Jianguo Zhao, Yanfang Wang   +4 more
wiley   +1 more source

Isoleucyl-tRNA synthetase 1 mutation impairs pulmonary surfactant homeostasis by disrupting alveolar macrophage function. [PDF]

Respir Res
Zhou W, Dai D, Chen Y, Han X, Dong X, Liao Y, Chen T, Wang H, He C, Lu Y, Zheng C, Zhou Y, Qian L.   +12 more
europepmc   +1 more source

Alveolar Macrophages [PDF]

, 2004
openaire   +1 more source

Human Fibroblast–Myeloid Cell Tissue Atlas Across the Lungs, Synovium, Skin, and Heart

Arthritis &Rheumatology, EarlyView.
Objective The availability of single‐cell RNA sequencing (scRNAseq) data in different tissues and disease states provides an opportunity to compare cellular subsets and identify common and unique cellular activation. In this study, we aimed to characterize shared and tissue‐specific myeloid and stromal phenotypes and to uncover key cellular subtypes ...
Lucy MacDonald, Katerina Apostolopoulou, Olympia Hardy, Melpomeni Toitou, Gabriela Kania, Przemyslaw Blyszczuk, Raphael Micheroli, Thomas D. Otto, Mariola Kurowska‐Stolarska, Caroline Ospelt   +9 more
wiley   +1 more source

Comparative Transcriptional Profiling of Key Macrophage and Fibroblast Subpopulations in Rheumatoid Arthritis–Associated Lung Disease

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) often involves extra‐articular complications, including interstitial lung disease (ILD) and/or pulmonary nodules. Transcriptomic profiling of lung tissue provides the opportunity to directly assess cell‐specific gene expression and corresponding pathway activation in different types of rheumatoid lung disease ...
Tracy Tabib, Ogechukwu Ezenwa, Joshua Sciurba, Eleanor B. Valenzi, John Sembrat, Brittany Cody, Jishnu Das, Robert Lafyatis, Dana P. Ascherman   +8 more
wiley   +1 more source

NRF2-mediated inhibition of alveolar macrophage MHC II expression during Mycobacterium tuberculosis infection. [PDF]

Cell Rep
Pham LK, Cervantes MM, Lim PN, Dubey D, Tufts A, Mitchell MC, Shinkawa T, Behar SM, Rothchild AC.   +8 more
europepmc   +1 more source