Results 141 to 150 of about 269,936 (310)

Genetics and Alzheimer's Disease [PDF]

, 1989
M J Owen
openalex   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

Advanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao, Tian Shen, Shengda Cao, Ziyi Liu, Wendu Pang, Meixuan Li, Jingjing Liu, Wen Li, Yunhao Wu, Chengcheng Liu, Ming Xia, Xiaolong Fu, Cheng Cheng   +12 more
wiley   +1 more source

Apolipoprotein E and Alzheimer's disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins

Journal of Lipid Research, 2017
Alzheimer's disease (AD) is one of the fastest-growing causes of death and disability in persons 65 years of age or older, affecting more than 5 million Americans alone.
Tien-Phat V. Huynh, Albert A. Davis, Jason D. Ulrich, David M. Holtzman   +3 more
doaj  

Alzheimer's disease: neuropathological correlates of cognitive and motor disorders

, 1987
P.K. Mölsä, Erkki Säkö, Leo Paljärvi, Juha O. Rinne, U. K. Rinne   +4 more
openalex   +1 more source

Lymphokine Production in Patients with Alzheimer's Disease [PDF]

, 1989
H. Bessler, P. Sirota, J. Hart, M Djaldetti   +3 more
openalex   +1 more source

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

Advanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao, Lin Zeng, Jiaren Wang, Chang Hong, Ziyong Zhang, Chengkai Wu, Hao Cui, Yan Li, Ruining Li, Shengxing Liang, Qijie Deng, Wenyuan Li, Xuejing Zou, Pengcheng Ma, Li Liu   +14 more
wiley   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Genetically determined Alzheimer's disease research advances: The Down Syndrome & Autosomal Dominant Alzheimer's Disease 2024 Conference. [PDF]

Alzheimers Dement
Falgàs N, Maure-Blesa L, Ances B, Flores-Aguilar L, Hartley S, Hassenstab J, Iulita MF, Janicki M, Koenig K, Lao P, Levin J, McDade E, Meijer L, Rafii MS, Snyder HM, Sánchez-Valle R, Fortea J, DSAD‐ADAD conference group, Arriola Infante J, Balasa M, Barroeta I, Barthelemy R N, Bejanin A, Benejam B, Bosch B, Bradshaw A, Carmona-Iragui M, Cohen A, Comas Albertí A, Csincsik L, Cuello AC, Del Hoyo Soriano L, Dijkstra J, Edwards N, Giménez S, Gonzalez-Ortiz F, Gordon B, Gutiérrez Fernández S, Handen B, Jacob C, Johnson E, Johansson C, Lladó A, Lleó A, Morabito S, Morcillo-Nieto AO, Montoliu-Gaya L, Okafor M, Pérez-Millan A, Potier MC, Ringman J, Rodríguez-Baz Í, Rubenstein E, Ryan NS, Strydom A, Vaqué-Alcázar L, Vermunt L, Videla Toro L, Zaman S.   +58 more
europepmc   +1 more source

Serum Parathyroid Hormone Concentrations in Senile Dementia (alzheimer's Disease)

, 1980
D Shore, M. R. Wills, J Savory, Richard Jed Wyatt   +3 more
openalex   +1 more source

A nose for Alzheimer's disease? [PDF]

, 1989
Jennifer Altman
openalex   +1 more source