Results 141 to 150 of about 472,310 (340)

Associations between APOE‐TOMM40 ‘523 haplotypes and limbic system white matter microstructure

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION We assessed associations between apolipoprotein E Translocase of Outer Mitochondrial Membrane 40 (APOE‐TOMM40)‐‘523 haplotypes and white matter microstructure (WMM) across limbic tracts important for memory and cognition in non‐Hispanic ...
Katelyn E. Mooney   +9 more
doaj   +1 more source

Clinical diagnosis of Alzheimer's disease [PDF]

open access: bronze, 1984
Guy M. McKhann   +5 more
openalex   +1 more source

Structure and Electrochemical Properties of ReS2‐LaFeO3 Nanocomposite for Dopamine Sensing

open access: yesAdvanced Sensor Research, EarlyView.
A novel ReS2‐LaFeO3 nanocomposite is developed for sensitive and reliable detection of dopamine (DA), an important neurotransmitter. The material performs well even in complex biological samples, demonstrating strong selectivity and accuracy. These findings highlight its potential for future applications in medical diagnostics and neuroscience research.
Obed Graham Keelson   +5 more
wiley   +1 more source

A SERS‐Based Antibody‐Aptamer Sandwich Assay for Extracellular Vesicle‐Associated Tau Detection Using Gold Nanoparticles

open access: yesAdvanced Sensor Research, EarlyView.
Tau protein plays a critical role in the pathology of Alzheimer's disease, utilizing extracellular vesicles (EVs) as a mechanism for intercellular transmission. This study develops a highly sensitive sandwich assay biosensor for detecting and quantifying tau‐associated EVs using surface‐enhanced Raman spectroscopy (SERS).
Saqer Al Abdullah   +6 more
wiley   +1 more source

Reduced dopamine-beta-hydroxylase activity in Alzheimer's disease [PDF]

open access: green, 1981
A.J. Cross   +5 more
openalex   +1 more source

Automated Transcranial Photobiomodulation in Healthy Rats: Effects on Working Memory and Brain Markers

open access: yesAdvanced Therapeutics, EarlyView.
Transcranial photobiomodulation (PBM) enhances spatial working memory in healthy rats under both continuous and alternating stimulation protocols. At the neural level, PBM modulates cytochrome c oxidase activity, increases prefrontal and hippocampal synaptic markers, and induces region‐specific c‐Fos expression. These effects suggest improved cognitive
Candela Zorzo   +6 more
wiley   +1 more source

ALZHEIMER'S DISEASE: A CASE REPORT WITH CEREBRAL BIOPSY AND ENYMATIC-HISTOCHEMICAL OBSERVATIONS

open access: bronze, 1963
Tadashi Miyake   +6 more
openalex   +2 more sources

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

open access: yesAdvanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar   +7 more
wiley   +1 more source

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