Results 121 to 130 of about 5,103,561 (270)

Changes in Alzheimer's disease blood biomarkers in kidney failure before and after kidney transplant

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Alzheimer's disease (AD) blood biomarkers show promise for clinical diagnosis but their reliability in chronic kidney disease (CKD) is debated. This study investigates the impact of kidney transplant (KT) on AD biomarkers in CKD.
Anneka E. Blankenship, Lauren Yoksh, Paul J. Kueck, Jonathan D. Mahnken, Jill K. Morris, Aditi Gupta   +5 more
doaj   +1 more source

Individuals With Multijoint Osteoarthritis Demonstrate Larger Longitudinal Declines in Frailty: Data From the Canadian Longitudinal Study on Aging

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to test the hypothesis that multijoint osteoarthritis would modify the relation between time and frailty progression, in which more affected joints would lead to larger declines over six years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell, Rebecca Moyer, Myles W. O'Brien   +2 more
wiley   +1 more source

A Scoping Review and Meta‐Analysis of Proportions of Central Nervous System Manifestations Reported in Patients with Sjögren's Disease

Arthritis Care &Research, Accepted Article.
Objective The objective of this scoping review was to synthesize evidence on the proportion of individuals living with Sjögren's disease who experience central nervous system (CNS) manifestations. Methods We searched MEDLINE (via PubMed) and Embase from 1980 through January 29, 2026, and the ECRI Guidelines Trust from 2020 through January 29, 2026 ...
Arun Varadhachary, Ghaith Noaiseh, Julie Frantsve‐Hawley, Frederick B. Vivino, Jennifer A. McCombe, Shamik Bhattacharyya, E. Sherwood Brown, Andrew R. Carey, Robert Fox, Thomas Grader‐Beck, Janet E. Lewis, Stephen Maitz, Steven Mandel, Astrid Rasmussen, George Sarka, R. Hal Scofield, Daniel J. Wallace, Rochelle Zak, Kristie Cox, Katherine M. Hammitt, Steven Carsons, Nancy Carteron   +21 more
wiley   +1 more source

Engineered Nanotopography to Modulate Growth and Signaling of Neuronal Networks

Advanced Functional Materials, EarlyView.
This study examines the interaction between neurons and nanoscale topographies on engineered substrates. Neurons cultured on nanowires, nanopillars and nanoneedles exhibit enhanced neurite outgrowth, form more organized neuronal circuits, and display improved synaptic connectivity, compared to flat substrates.
Hao Nguyen Tran, Kalyan Shobhana, Zlatan Trifunovic, Dan Smith, Michael Stuiber, Chennupati Jagadish, Mirella Dottori, Andrea J. O'Connor, Vini Gautam   +8 more
wiley   +1 more source

Fiscal Year 2012

, 2012
Annual financial report of the Texas Council on Alzheimer's Disease and Related Disorders documenting income, expenditures, and other relevant financial information for fiscal year ...
Texas Council on Alzheimer's Disease & Related Disorders
core  

Subjective cognitive complaints and decline among aging individuals with prior repetitive head impact exposure

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Subjective cognitive complaints (SCC) can precede Alzheimer's disease and related dementias. SCC in the absence of objective impairment is termed subjective cognitive decline (SCD). This study aimed to characterize SCC and SCD among a sample
Anna Aaronson, Monica T. Ly, Yorghos Tripodis, Caroline Altaras, Steven Lenio, Chad W. Farris, Christopher J. Nowinski, Maureen K. O'Connor, Brett M. Martin, Joseph N. Palmisano, Rachel L. Nosheny, Katherine A. Gifford, Eric G. Steinberg, Katherine W. Turk, Andrew E. Budson, Thor D. Stein, Ann C. McKee, Jesse Mez, Michael L. Alosco   +18 more
doaj   +1 more source

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

Brain and blood transcriptome-wide association studies identify five novel genes associated with Alzheimer's disease

BackgroundGenome-wide association studies (GWAS) have identified numerous genetic variants associated with Alzheimer's disease (AD), but their functional implications remain unclear.
Bush, William S, Naj, Adam C, Below, Jennifer E, Griswold, Anthony J, Alzheimer's Disease Genetics Consortium, Mews, Makaela A   +5 more
core   +1 more source

Age-disproportionate atrophy in Alzheimer's disease and Parkinson's disease spectra [PDF]

INTRODUCTION: Brain age gap (BAG), defined as the difference between MRI-predicted ‘brain age’ and chronological age, can capture information underlying various neurological disorders. We investigated the pathophysiological significance of the BAG across
Nobuo Fuse, Matsushima, Toma, Teruyuki Matsuoka, Takamura, Tsunehiko, Toma Matsushima, Kazuaki Kanai, Hanakawa, Takashi, Kanai, Kazuaki, Toshiya Murai, Noritaka Wakasugi, Mugikura, Shunji, Yoshinaga, Kenji, Atsushi Sekiguchi, Mitsunari Abe, Hiroshi Hoshino, Hoshino, Hiroshi, Murai, Toshiya, Tohoku Medical Megabank Brain Magnetic Resonance Imaging Study (TMMbMRI)Parkinson's and Alzheimer's disease Dimensional Neuroimaging Initiative (PADNI), Wakasugi, Noritaka, Nobukatsu Sawamoto, Toshiki Mizuno, Takashi Hanakawa, Togo, Hiroki, Kenji Yoshinaga, Shunji Mugikura, Sawamoto, Nobukatsu, Mizuno, Toshiki, Matsuoka, Teruyuki, Hiroki Togo, Tsunehiko Takamura, Abe, Mitsunari, Fuse, Nobuo, Sekiguchi, Atsushi   +32 more
core   +1 more source