Results 131 to 140 of about 5,103,561 (270)

Characterization of barriers and facilitators to recruiting veterans to participate in Alzheimer's disease biomarker research: a cross‐sectional survey

open access: yesAlzheimer’s & Dementia: Behavior & Socioeconomics of Aging
INTRODUCTION This study examined veteran‐specific factors affecting interest in Alzheimer's disease and related dementias (ADRD) biomarker research participation.
Ralph Richards   +13 more
doaj   +1 more source

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

open access: yesAdvanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão   +5 more
wiley   +1 more source

Alzheimer’s disease [PDF]

open access: yesPostgraduate Medical Journal, 1995
P, Kist, I R, Hastie
openaire   +2 more sources

Elastomeric 3D‐Printed Microenvironments Enable Nanonewton Force Measurements in Healthy and Diseased Human Pluripotent Stem Cell‐Derived Neuroepithelial Cells

open access: yesAdvanced Materials, EarlyView.
We present elastomeric three‐dimensional (3D) microstructures fabricated via two‐photon polymerization (2PP) and post‐processed through wet etching, for quantifying nanonewton (nN)‐scale forces applied by healthy and diseased neural cells. The mechanically characterized free‐standing beam architectures enable measurement of traction forces of ...
Pieter F. J. van Altena   +7 more
wiley   +1 more source

Fiscal Year 2014

open access: yes, 2014
Annual financial report of the Texas Council on Alzheimer's Disease and Related Disorders documenting income, expenditures, and other relevant financial information for fiscal year ...
Texas Council on Alzheimer's Disease & Related Disorders
core  

Donanemab-associated clinical improvement in Alzheimer's disease presenting predominantly with neuropsychiatric symptoms: A case report

open access: yesJournal of Alzheimer's Disease Reports
Late-life depression may mask Alzheimer's disease (AD). We report a 78-year-old man with treatment-refractory depressive and anxiety symptoms accompanied by paroxysmal somatic attacks, unresponsive to psychotropic treatment and modified electroconvulsive
Yehao Jiang   +3 more
doaj   +1 more source

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

open access: yesAdvanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian   +7 more
wiley   +1 more source

Benefits of Donepezil on Cognition, Function and Neuropsychiatric Symptoms in Patients with Mild and Moderate Alzheimer's Disease over One Year

open access: yes, 2001
The results of this 1‐year, multinational, double‐blind, placebo‐controlled study of an acetylcholinesterase inhibitor confirm the beneficial effects of donepezil on cognition, activities of daily living and behavioral symptoms over 1 year in the ...
Verhey, F   +9 more
core   +1 more source

Alzheimer Disease [PDF]

open access: yesDisease-a-Month, 2010
Rudy J, Castellani   +2 more
openaire   +2 more sources

Recent Advances in Transparent Microelectrode Device Architecture and Fabrication Strategies for Biomedical Applications

open access: yesAdvanced Materials Technologies, EarlyView.
Transparent microelectrode arrays enable simultaneous optical and electrical electrophysiology with high spatiotemporal resolution, allowing multimodal observations of dynamic biological systems. Advances in materials and device architectures improve device performance by addressing key trade‐offs between optical transparency, impedance, and ...
Michael Abraham Listyawan   +6 more
wiley   +1 more source

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