Results 171 to 180 of about 340,510 (279)

Four decades of Alzheimer's disease discoveries, data, and research resources: The NIH Alzheimer's Disease Research Center Program. [PDF]

Alzheimers Dement
Donley G, Hsiao J, Balintfy J, Silverberg N.   +3 more
europepmc   +1 more source

A Synergistic Hydrogel‐Microalgae Platform for Dual‐Targeting of Intestinal and Neuroimmune Dysfunction in Inflammatory Bowel Disease

Advanced Science, EarlyView.
A bioactive hydrogel incorporating Chlorella vulgaris and paeoniflorin within a carboxymethyl chitosan/sodium alginate matrix cross‐linked with genipin is developed for inflammatory bowel disease therapy. The hydrogel exhibits gastric stability and intestine‐responsive release.
Jing Lu, Kangyu Jin, Bing Chen, Ruoxi Wang, Fengling Hu, Shaohua Hu, Danni Zhong, Xiaoming Li, Min Zhou   +8 more
wiley   +1 more source

Environmental causes and prevention measures for Alzheimer's disease /

This book examines the increased incidence of the disease in developed countries, and provides new insights into environmental causation, primarily metals.Includes bibliographical references and index.1. Introduction -- 2. A little background on dementia
Brewer, George J.author.
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Clinical Phenotype of G206d Mutation in the Presenilin 1 Gene in Pathologically Confirmed Familial Alzheimer's Disease

, 2012
Familial Alzheimer's disease (FAD) is genetically heterogeneous, autosomal dominant, with nearly 100% penetrance. In FAD, most common causative genetic mutations are presenilin 1 (PSEN1), presenilin 2 and amyloid-beta protein precursor.
吳亞縈;鄭菡若;李進成;邱銘章;李銘仁;陳達夫;徐榮隆, WU, YA-YING;CHENG, IRENE HAN-JUO;LEE, CHIN-CHENG;CHIU, MING-JANG;LEE, MING-JEN;CHEN, TA-FU;HSU, JUNG-LUNG   +1 more
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FDA Approval of Donanemab-azbt: A New Dawn in Alzheimer's Disease Treatment. [PDF]

Health Sci Rep
Riaz R, Fatima M, Ramzan S, Rathi D, Fatima F, Farooq M, Shaukat A, Khaliq N, Akilimali A.   +8 more
europepmc   +1 more source

Orthogonal Ionic Liquid‐Based Extraction Strategy Enables Amyloid‐Specific Profiling of Aggregate Proteome

Advanced Science, EarlyView.
An orthogonal ionic‐liquid extraction (Orth‐iEA) enables selective isolation of amyloid fibrils. TMGBF4 disrupts hydrogen‐bonded β‐sheet networks to solubilize amyloid aggregates, whereas C12ImCl interacts with hydrophobic regions of non‐amyloid proteins.
Shiying Zheng, Ye Liu, Bowen Zhong, Huiying Chu, Zhou Gong, Baofeng Zhao, Mengchun Cheng, Zhen Liang, Yukui Zhang, Qun Zhao, Lihua Zhang   +10 more
wiley   +1 more source

THE ALZHEIMER’S DISEASE MULTIFACTORIAL THERAPEUTIC AGENT E2F4DN PREVENTS THE UPREGULATION OF THE PRO-DEATH GENE CITED 2 IN RESPONSE TO DNA DAMAGE IN NEURONS

IBRO Neuroscience Reports, 2023
Aina Maria Llabrés Mas, Alberto Garrido García, Vanesa Cano Daganzo, Jose María Frade   +3 more
doaj   +1 more source

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

Advanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer   +10 more
wiley   +1 more source

Memory loss, Alzheimer's disease, and dementia : a practical guide for clinicians /

Now presented in full color, this updated edition of Memory Loss, Alzheimer's Disease, and Dementia is designed as a practical guide for clinicians that delivers the latest treatment approaches and research findings for dementia and related illnesses ...
Preceeded by:Budson, Andrew E.Memory loss.2011., Budson, Andrew E.,author., Solomon, Paul R.,author.   +2 more
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Pharmacological Treatment of Alzheimer's Disease

, 2017
Dementia is one of the most common manifestations in the elderly in the western world. Although it can have various causes such as Vascular Dementia, Lewy body dementia, Parkinsonian dementia and frontotemporal dementia, the most common form of dementia ...
Waleed, Muhammad
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