Results 201 to 210 of about 9,230,509 (381)

Genetics and Alzheimer's Disease [PDF]

, 1989
M J Owen
openalex   +1 more source

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

Advanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong, Pei Li, Yi Jiang, Zhihan Wang, Shihui Fu, Hebin Che, Meng Liu, Xiaojing Zhao, Chunlei Liu, Chenghui Zhao, Qin Zhong, Chongyou Rao, Siwei Wang, Suyuan Liu, Dayu Hu, Dongjin Wang, Juntao Gao, Kai Guo, Xinwang Liu, En Zhu, Kunlun He   +20 more
wiley   +1 more source

Long-term metformin use for Alzheimer's disease prevention? [PDF]

Alzheimers Dement
Daly T, Imbimbo BP.
europepmc   +1 more source

Clinical Aspects of Alzheimer's Disease and Senile Dementia (Aging, Vol 15) [PDF]

, 1981
John Pearce
openalex   +1 more source

Simultaneous Monitoring of Tyrosinase and ATP in Thick Brain Tissues Using a Single Two‐Photon Fluorescent Probe

Advanced Science, EarlyView.
A single dual‐emission two‐photon fluorescent probe is designed for simultaneously tracking tyrosinase (TYR) and adenosine triphosphate (ATP). With the help of this probe, the intricate correlation and regulatory mechanism between TYR and ATP during oxidative stress is uncovered.
Hong Huang, Huiru Li, Yong Zhang, Xuhan Xia, Ningwen Zhang, Haixin Fan, Longhua Guo, Yongyong Cao, Hu Pan, Ruijie Deng, Yangang Wang, Rodrigo Ledesma‐Amaro, Jianguo Xu   +12 more
wiley   +1 more source

Clinically meaningful outcomes in Alzheimer's disease and Alzheimer's disease related dementias trials. [PDF]

Alzheimers Dement (N Y)
Stoeckel LE, Fazio EM, Hardy KK, Kidwiler N, McLinden KA, Williams B.   +5 more
europepmc   +1 more source

Tetrahydroaminoacridine in Alzheimer's disease. [PDF]

, 1989
P. V. Scott, M. de Jong
openalex   +1 more source

Role of Testosterone Signaling in Microglia: A Potential Role for Sex‐Related Differences in Alzheimer's Disease

Advanced Science, EarlyView.
Testosterone enhances Aβ‐induced autophagy in microglia via the non‐genomic testosterone receptor GPRC6A, promoting Aβ clearance by suppressing ERK phosphorylation and inhibiting mTOR activation. In male 5xFAD mice, testicular removal reduces microglial autophagy and Aβ clearance, which is restored by testosterone.
Haiyan Du, Akiko Mizokami, Junjun Ni, Simeng Zhang, Yosuke Yamawaki, Tomomi Sano, Eijiro Jimi, Isei Tanida, Takashi Kanematsu   +8 more
wiley   +1 more source

Alzheimer's Disease [PDF]

Annual Review of Public Health, 1989
B T, Hyman, H, Damasio, A R, Damasio, G W, Van Hoesen   +3 more
openaire   +2 more sources

Integrity of Semantic Fields in Alzheimer's Disease

, 1988
Robert D. Nebes, Christopher B. Brady
openalex   +1 more source