Results 31 to 40 of about 9,230,509 (381)

Microbes and Alzheimer’s Disease

Journal of Alzheimer's Disease, 2016
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Judith A. Whittum-Hudson, Angela R. Kamer, Claudio Grassi, Luc Letenneur, Alan P. Hudson, Kelly Del Tredici, Naji Tabet, Jürgen Haas, Hugo Lövheim, Ruth F. Itzhaki, Ruth F. Itzhaki, Chris M. Preston, Brian J. Balin, María J. Bullido, Elaine L. Bearer, Tamas Fulop, Roberta Mancuso, Simon D. Taylor-Robinson, Richard Lathe, Anna Teresa Palamara, George Perry, Timo E. Strandberg, Carola Otth, Heiko Braak, Mario Clerici, S. Louise Cosby, Judith Miklossy, C.J. Carter, Federico Licastro, W. Sue T. Griffin, Etheresia Pretorius, Hugh J. Field, Melvyn J. Ball, Douglas B. Kell   +33 more
openaire   +11 more sources

On the reconceptualization of Alzheimer’s disease [PDF]

Bioethics, 2018
AbstractIn the hope of future treatments to prevent or slow down the disease, there is a strong movement towards an ever‐earlier detection of Alzheimer’s disease (AD). In conjunction with scientific developments, this has prompted a reconceptualization of AD, as a slowly progressive pathological process with a long asymptomatic phase. New concepts such
Maartje H. N. Schermer, Edo Richard
openaire   +6 more sources

Differentiating among stages of cognitive impairment in aging: Version 3 of the Uniform Data Set (UDS) neuropsychological test battery and MoCA index scores

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2020
Introduction Federally funded Alzheimer's Disease Centers in the United States have been using a standardized neuropsychological test battery as part of the National Alzheimer's Coordinating Center Uniform Data Set (UDS) since 2005. Version 3 (V3) of the
Hiroko H. Dodge, Felicia C. Goldstein, Nicole I Wakim, Tamar Gefen, Merilee Teylan, Kwun C.G. Chan, Walter A. Kukull, Lisa L. Barnes, Bruno Giordani, Timothy M. Hughes, Joel H. Kramer, David A. Loewenstein, Daniel C. Marson, Dan M. Mungas, Nora Mattek, Bonnie C. Sachs, David P. Salmon, Monica Willis‐Parker, Kathleen A. Welsh‐Bohmer, Katherine V. Wild, John C. Morris, Sandra Weintraub, National Alzheimer's Coordinating Center (NACC)   +22 more
doaj   +1 more source

Accelerating diversity in Alzheimer's disease research by partnering with a community advisory board

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2023
Introduction Community advisory boards (CABs) and researcher partnerships present a promising opportunity to accelerate enrollment of underrepresented groups (URGs).
Alex Pena‐Garcia, Ralph Richards, Mollie Richards, Christopher Campbell, Hank Mosley, Joseph Asper, Johanne Eliacin, Angelina Polsinelli, Liana Apostolova, Hugh Hendrie, Andrew Tackett, Caprice Elliott, Sarah Van Heiden, Sujuan Gao, Andrew Saykin, Sophia Wang, IADRC CAB   +16 more
doaj   +1 more source

EEG UPPER/LOW ALPHA FREQUENCY POWER RATIO RELATES TO TEMPORO-PARIETAL BRAIN ATROPHY AND MEMORY PERFORMANCES IN MILD COGNITIVE IMPAIRMENT

Frontiers in Aging Neuroscience, 2013
Objective: temporo-parietal cortex thinning is associated to mild cognitive impairment (MCI) due to Alzheimer disease (AD). The increase of EEG upper/low alpha power ratio has been associated with AD-converter MCI subjects.
Davide Vito Moretti, donata epaternicò, Giuliano eBinetti, Orazio eZanetti, giovanni b Frisoni   +4 more
doaj   +1 more source

Investigating Conversion from Mild Cognitive Impairment to Alzheimer's Disease using Latent Space Manipulation [PDF]

arXiv, 2021
Alzheimer's disease is the most common cause of dementia that affects millions of lives worldwide. Investigating the underlying causes and risk factors of Alzheimer's disease is essential to prevent its progression. Mild Cognitive Impairment (MCI) is considered an intermediate stage before Alzheimer's disease.
arxiv  

Association of Heel Bone Mineral Density With Incident Disability and Mortality in Community‐Dwelling Older Adults

JBMR Plus, 2020
Age‐related bone loss is common in older adults. However, the association of low bone mass with incident disability and mortality is not well established.
Ryan D Ross, Raj C Shah, Sue E Leurgans, Aron S Buchman, David A Bennett   +4 more
doaj   +1 more source

The Alzheimer's disease neuroimaging initiative (ADNI): MRI methods

Journal of Magnetic Resonance Imaging, 2008
The Alzheimer's Disease Neuroimaging Initiative (ADNI) is a longitudinal multisite observational study of healthy elders, mild cognitive impairment (MCI), and Alzheimer's disease.
C. Jack, M. Bernstein, Nick C Fox, Paul M. Thompson, G. Alexander, D. Harvey, B. Borowski, P. Britson, Jennifer L Whitwell, C. Ward, A. Dale, J. Felmlee, J. Gunter, D. Hill, R. Killiany, N. Schuff, Sabrina Fox‐Bosetti, Chen Lin, C. Studholme, C. DeCarli, G. Krueger, H. Ward, G. Metzger, K. T. Scott, R. Mallozzi, D. Blezek, J. Levy, J. Debbins, A. Fleisher, M. Albert, R. Green, G. Bartzokis, G. Glover, J. Mugler, M. Weiner   +34 more
semanticscholar   +1 more source

Isoform-selective decrease of glycogen synthase kinase-3-beta (GSK-3β) reduces synaptic tau phosphorylation, transcellular spreading, and aggregation

iScience, 2021
Summary: It has been suggested that aberrant activation of glycogen synthase kinase-3-beta (GSK-3β) can trigger abnormal tau hyperphosphorylation and aggregation, which ultimately leads to neuronal/synaptic damage and impaired cognition in Alzheimer ...
Ana Claudia Amaral, Beatriz G. Perez-Nievas, Michael Siao Tick Chong, Alicia Gonzalez-Martinez, Herminia Argente-Escrig, Sara Rubio-Guerra, Caitlin Commins, Serra Muftu, Bahareh Eftekharzadeh, Eloise Hudry, Zhanyun Fan, Prianca Ramanan, Shuko Takeda, Matthew P. Frosch, Susanne Wegmann, Teresa Gomez-Isla   +15 more
doaj  

Toward a multimodal multitask model for neurodegenerative diseases diagnosis and progression prediction [PDF]

, 2021
Recent studies on modelling the progression of Alzheimer's disease use a single modality for their predictions while ignoring the time dimension. However, the nature of patient data is heterogeneous and time dependent which requires models that value these factors in order to achieve a reliable diagnosis, as well as making it possible to track and ...
arxiv   +1 more source