Results 111 to 120 of about 9,392,963 (368)
Variant of TREM2 associated with the risk of Alzheimer's disease.
BACKGROUND Sequence variants, including the ε4 allele of apolipoprotein E, have been associated with the risk of the common late-onset form of Alzheimer's disease.
Thorlákur Jónsson+23 more
semanticscholar +1 more source
Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen+9 more
wiley +1 more source
Synaptic vesicle-omics in mice captures signatures of aging and synucleinopathy
Neurotransmitter release occurs through exocytosis of synaptic vesicles. α-Synuclein’s function and dysfunction in Parkinson’s disease and other synucleinopathies is thought to be tightly linked to synaptic vesicle binding. Age is the biggest risk factor
Virginia Gao+15 more
doaj +1 more source
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu+7 more
wiley +1 more source
Living with Alzheimer’s Disease: A Wife’s Perspective [PDF]
Bethany Chaffin
openalex +1 more source
PND99 A STUDY OF PREFERENCES FOR DISEASE-MODIFYING TREATMENTS FOR ALZHEIMER’S DISEASE
H.M. Fillit+5 more
openaire +2 more sources
The neuropathological diagnosis of Alzheimer’s disease
Alzheimer’s disease is a progressive neurodegenerative disease most often associated with memory deficits and cognitive decline, although less common clinical presentations are increasingly recognized.
M. DeTure, D. Dickson
semanticscholar +1 more source
This study introduces a controllable degradation system for Mg‐based biomaterials using sputtering technology, marking a significant advancement in nerve regeneration research. The Mg‐sputtered nerve conduits demonstrate enhanced biocompatibility, biofunctionality, mechanical compatibility, and precise magnesium release, resulting in improved axonal ...
Hyewon Kim+12 more
wiley +1 more source
Table S1. List of all antibodies used, with respective working dilutions for either WB or IHF, as well as Companies of origin and catalog number specification. (PDF 290 kb)
Benedetto, Giulia Di+8 more
openaire +1 more source
In this study we examined changes in the large-scale structure of resting-state brain networks in patients with Alzheimer's disease compared with non-demented controls, using concepts from graph theory.
R. Helmich+193 more
semanticscholar +1 more source