Results 151 to 160 of about 530,865 (344)
Ultrasensitive Detection of FKBP12 Using a Synthetic Receptor‐Functionalized QCM Nanoplatform
Advanced Sensor Research, EarlyView.A reusable nanosensor platform for ultralow FKBP12 detection in physiological fluids is presented. Combining a gold‐coated QCM with a custom‐designed receptor in a self‐assembled monolayer, the device achieves picomolar sensitivity and high selectivity.Martina Tozzetti, Maria Raffaella Martina, Giacomo Lucchesi, Kristian Vasa, Ahtsham Ishaq, Laura Marsili, Piero Procacci, Stefano Menichetti, Gabriella Caminati +8 morewiley +1 more sourceLiquiritin Exerts a Dual Effect on BMSCs Osteogenic Differentiation and Fracture Healing by Activating the ERK/JNK Pathway and Providing Antioxidant Protection
Advanced Therapeutics, EarlyView.Liquiritin enhances the osteogenic differentiation of BMSCs and promotes fracture healing through the activation of the ERK/JNK signaling pathway and by exerting antioxidant protective effects. Abstract
Liquiritin, a flavonoid from Glycyrrhiza uralensis L., has diverse pharmacological properties, but its impact on fracture healing is unexplored.Haijun Mao, Jing Liu, Juan Feng, Yalikun Yusufu, Lei Yang, Qing Jiang, Minghui Sun +6 morewiley +1 more sourceAutomated Transcranial Photobiomodulation in Healthy Rats: Effects on Working Memory and Brain Markers
Advanced Therapeutics, EarlyView.Transcranial photobiomodulation (PBM) enhances spatial working memory in healthy rats under both continuous and alternating stimulation protocols. At the neural level, PBM modulates cytochrome c oxidase activity, increases prefrontal and hippocampal synaptic markers, and induces region‐specific c‐Fos expression. These effects suggest improved cognitive Candela Zorzo, Lucía Rodríguez‐Fernández, Emily Gabriela Castillo‐Escalona, Juan A. Martínez, Laura Mañas, Natalia Arias, Jorge L. Arias +6 morewiley +1 more sourceGenetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
Nature Genetics, 2019 B. Kunkle, B. Grenier‐Boley, R. Sims, J. Bis, V. Damotte, A. Naj, A. Boland, M. Vronskaya, S. J. van der Lee, A. Amlie-Wolf, C. Bellenguez, A. Frizatti, V. Chouraki, E. Martin, K. Sleegers, N. Badarinarayan, J. Jakobsdóttir, K. Hamilton-Nelson, S. Moreno-Grau, R. Olaso, R. Raybould, Yuning Chen, A. Kuzma, M. Hiltunen, T. Morgan, S. Ahmad, B. Vardarajan, J. Epelbaum, P. Hoffmann, M. Boada, G. Beecham, Jean-Guillaume Garnier, D. Harold, A. Fitzpatrick, O. Valladares, Marie-Laure Moutet, A. Gerrish, A. Smith, L. Qu, D. Bacq, N. Denning, X. Jian, Yi Zhao, M. Del Zompo, Nick C Fox, S. Choi, I. Mateo, J. T. Hughes, H. Adams, J. Malamon, F. Sánchez-García, Y. Patel, Jennifer A. Brody, B. Dombroski, M. Naranjo, M. Daniilidou, G. Eiriksdottir, Shubhabrata Mukherjee, D. Wallon, J. Uphill, T. Aspelund, L. Cantwell, F. Garzia, D. Galimberti, E. Hofer, Mariusz Butkiewicz, B. Fin, E. Scarpini, C. Sarnowski, W. Bush, S. Meslage, J. Kornhuber, Charles C. White, Yuenjoo Song, R. Barber, S. Engelborghs, S. Sordon, D. Voijnovic, P. Adams, R. Vandenberghe, M. Mayhaus, L. Cupples, M. Albert, P. D. de Deyn, W. Gu, J. Himali, D. Beekly, A. Squassina, A. Hartmann, A. Orellana, D. Blacker, E. Rodríguez-Rodríguez, S. Lovestone, M. Garcia, R. Doody, Carmen Munoz-Fernadez, R. Sussams, Honghuang Lin, T. Fairchild, Y. A. Benito, C. Holmes, Hata Karamujić‐Čomić, M. Frosch, H. Thonberg, W. Maier, G. Roschupkin, B. Ghetti, V. Giedraitis, A. Kawalia, Shuo Li, R. Huebinger, L. Kilander, S. Moebus, I. Hernández, M. Kamboh, R. Brundin, J. Turton, Qiong Yang, M. Katz, L. Concari, J. Lord, A. Beiser, C. Keene, S. Helisalmi, I. Kloszewska, W. Kukull, A. Koivisto, A. Lynch, L. Tárraga, E. Larson, A. Haapasalo, B. Lawlor, T. Mosley, R. Lipton, V. Solfrizzi, M. Gill, W. Longstreth, T. Montine, V. Frisardi, M. Diez-Fairen, F. Rivadeneira, R. Petersen, V. Deramecourt, I. Álvarez, Francesca Salani, A. Ciaramella, E. Boerwinkle, E. Reiman, N. Fievet, J. Rotter, J. Reisch, O. Hanon, C. Cupidi, A. G. Andre Uitterlinden, D. Royall, C. Dufouil, R. Maletta, I. de Rojas, M. Sano, A. Brice, R. Cecchetti, P. George-Hyslop, K. Ritchie, M. Tsolaki, D. Tsuang, B. Dubois, D. Craig, Chuang‐Kuo Wu, H. Soininen, D. Avramidou, R. Albin, L. Fratiglioni, A. Germanou, L. Apostolova, L. Keller, M. Koutroumani, S. Arnold, F. Panza, O. Gkatzima, S. Asthana, D. Hannequin, P. Whitehead, C. Atwood, P. Caffarra, H. Hampel, I. Quintela, Á. Carracedo, L. Lannfelt, D. Rubinsztein, L. Barnes, F. Pasquier, L. Frölich, S. Barral, B. McGuinness, T. Beach, J. Johnston, J. Becker, P. Passmore, E. Bigio, J. Schott, T. Bird, J. Warren, B. Boeve, Michelle K. Lupton, J. Bowen, P. Proitsi, A. Boxer, J. Powell, J. Burke, J. Kauwe, J. Burns, M. Mancuso, J. Buxbaum, U. Bonuccelli, N. Cairns, A. McQuillin, C. Cao, G. Livingston, C. Carlson, N. Bass, C. Carlsson, J. Hardy, R. Carney, J. Bras, M. Carrasquillo, R. Guerreiro, M. Allen, H. Chui, E. Fisher, C. Masullo, E. Crocco, C. DeCarli, G. Bisceglio, M. Dick, Li Ma, R. Duara, N. Graff-Radford, Denis A. Evans, A. Hodges, K. Faber, M. Scherer, K. Fallon, M. Riemenschneider, D. Fardo, R. Heun, M. Farlow, H. Kölsch, S. Ferris, M. Leber, T. Foroud, I. Heuser, D. Galasko, I. Giegling, M. Gearing, M. Hüll, D. Geschwind, J. Gilbert, J. Morris, R. Green, K. Mayo, J. Growdon, T. Feulner, R. Hamilton, L. Harrell, D. Drichel, L. Honig, T. Cushion, M. Huentelman, P. Hollingworth, C. Hulette, B. Hyman, R. Marshall, G. Jarvik, A. Meggy, E. Abner, G. Menzies, Lee‐way Jin, G. Leonenko, L. Real, G. Jun, C. Baldwin, D. Grozeva, A. Karydas, G. Russo, J. Kaye, R. Kim, F. Jessen, N. Kowall, B. Vellas, J. Kramer, E. Vardy, F. LaFerla, K. Jöckel, J. Lah, M. Dichgans, J. Leverenz, D. Mann, A. Levey, S. Pickering-Brown, A. Lieberman, N. Klopp, K. Lunetta, H. Wichmann, C. Lyketsos, K. Morgan, D. Marson, K. Brown, F. Martiniuk, C. Medway, D. Mash, M. Nöthen, E. Masliah, N. Hooper, W. McCormick, A. Daniele, S. McCurry, A. Bayer, A. McDavid, J. Gallacher, A. Mckee, H. van den Bussche, M. Mesulam, C. Brayne, B. Miller, S. Riedel-Heller, C. Miller, Joshua W. Miller, A. Al-Chalabi, J. Morris, C. Shaw, A. Myers, J. Wiltfang, S. O'Bryant, J. Olichney, V. Álvarez, J. Parisi, A. Singleton, H. Paulson, J. Collinge, W. Perry, S. Mead, E. Peskind, D. Cribbs, M. Rossor, A. Pierce, N. Ryan, W. Poon, B. Nacmias, H. Potter, S. Sorbi, J. Quinn, E. Sacchinelli, A. Raj, G. Spalletta, M. Raskind, C. Caltagirone, P. Bossù, M. D. Orfei, B. Reisberg, R. Clarke, C. Reitz, A. Smith, J. Ringman, D. Warden, E. Roberson, G. Wilcock, E. Rogaeva, A. Bruni, H. Rosen, M. Gallo, R. Rosenberg, Y. Ben-Shlomo, M. Sager, P. Mecocci, A. Saykin, P. Pastor, M. Cuccaro, J. Vance, J. Schneider, L. S. Schneider, S. Slifer, W. Seeley, Amanda G. Smith, J. Sonnen, S. Spina, R. Stern, R. Swerdlow, Mitchell Tang, R. Tanzi, J. Trojanowski, J. Troncoso, V. V. Van Deerlin, L. V. Van Eldik, H. Vinters, J. Vonsattel, S. Weintraub, K. Welsh-Bohmer, K. Wilhelmsen, J. Williamson, T. Wingo, R. Woltjer, C. Wright, Chang-En Yu, Lei Yu, Y. Saba, A. Pilotto, M. Bullido, O. Peters, P. Crane, D. Bennett, P. Bosco, E. Coto, V. Boccardi, P. D. De Jager, A. Lleó, N. Warner, O. Lopez, M. Ingelsson, P. Deloukas, Carlos Cruchaga, C. Graff, R. Gwilliam, M. Fornage, A. Goate, P. Sánchez-Juan, P. Kehoe, N. Amin, N. Ertekin-Taner, C. Berr, S. Debette, S. Love, L. Launer, S. Younkin, J. Dartigues, C. Corcoran, M. Ikram, D. Dickson, G. Nicolas, D. Campion, J. Tschanz, H. Schmidt, H. Hakonarson, J. Clarimón, R. Munger, R. Schmidt, L. Farrer, C. van Broeckhoven, Michael C. O’Donovan, A. Destefano, L. Jones, J. Haines, J. Deleuze, M. Owen, V. Gudnason, R. Mayeux, V. Escott-Price, B. Psaty, A. Ramírez, Li-San Wang, A. Ruiz, C. V. van Duijn, P. Holmans, S. Seshadri, Julie Williams, P. Amouyel, G. Schellenberg, J. Lambert, M. Pericak-Vance +467 moresemanticscholar +1 more sourceRewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
Advanced Therapeutics, EarlyView.This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen +7 morewiley +1 more source
