Results 221 to 230 of about 317,693 (354)

Cognitive and behavioural predictors of survival in Alzheimer disease:results from a sample of treated patients in a tertiary-referral memory clinic [PDF]

, 2012
Agüero-Torres, Andersen, Brandt, Brookmeyer, Buchner, Cox, Cummings, Doody, Ferri, Folstein, Gambassi, General Register Office for Scotland, Helmer, Hicks, Hötte, Inouye, ISD Scotland, Kaplan, Knopman, Landi, Larson, Lawton, Lezak, Luchsinger, Martyn, McGurn, McKhann, Mental Welfare Commission for Scotland, Mielke, Miller, Morgan, Musicco, Nelson, Newcomer, Rait, Reisberg, Richards, Robbins, Scarmeas, Scarmeas, Schneider, Sinforiani, Solfrizzi, SPSS Inc, Starr, Starr, Starr, Starr, Stern, Stern, Stern, Stern, Thomas, Tsai, Tun, Van Dijk, Wang, Whalley, Whitmer, Wolfson   +59 more
core   +1 more source

Apolipoprotein E ϵ4 Allele and Familial Aggregation of Alzheimer Disease [PDF]

, 1998
María Martínez, Dominique Campion, Alexis Brice, Didier Hannequin, Bruno Dubois, Olivier Didierjean, Agnès Michon, Catherine Thomas-Antérion, Michèle Puel, Thierry Frébourg, Y. Agid, Françoise Clerget‐Darpoux   +11 more
openalex   +1 more source

Nanoplasmonic Infrared Microarray Sensor Enabling Structural Protein Biomarker‐Based Drug Screening for Neurodegenerative Diseases

Advanced Science, EarlyView.
This work introduces an on‐chip, integrated plasmonic infrared microarray sensor that enables high‐throughput, label‐free drug screening targeting structural protein biomarkers in neurodegenerative diseases. Through ultra‐compact microwell arrays, the sensor achieves ultra‐sensitive, rapid, and multiplexed secondary structural analysis of the effect of
Deepthy Kavungal, Enzo Morro, Senthil T Kumar, Berkay Dagli, Hilal A Lashuel, Hatice Altug   +5 more
wiley   +1 more source

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

Advanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich, Jing Wang, Ferdinand Althammer, Tim Schubert, Nina Kluck, Valery Grinevich, Stefanie Schmitteckert, Christian P. Schaaf, Gudrun A. Rappold   +8 more
wiley   +1 more source

A novel neuroimaging based early detection framework for alzheimer disease using deep learning. [PDF]

Sci Rep
Alasiry A, Shinan K, Alsadhan AA, Alhazmi HE, Alanazi F, Ashraf MU, Muhammad T.   +6 more
europepmc   +1 more source

The seven-transmembrane spanning topography of the Alzheimer disease-related presenilin proteins in the plasma membranes of cultured cells

, 1997
Nazneen N. Dewji, Sherwin J. Singer
openalex   +1 more source

Should Alzheimers Disease Patients Be Allowed to Drive? A Medical, Legal, and Ethical Dilemna [PDF]

, 1996
Michael L. Freedman, Deborah L. Freedman
openalex   +1 more source

Bacteroides Fragilis‐Derived Outer Membrane Vesicles Deliver MiR‐5119 and Alleviate Colitis by Targeting PD‐L1 to Inhibit GSDMD‐Mediated Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
Bacteroides fragilis‐derived outer membrane vesicles deliver miR‐5119 and alleviate colitis by targeting PD‐L1 to inhibit GSDMD‐mediated neutrophil extracellular trap formation. Abstract Inflammatory bowel disease (IBD) results from a breakdown in the symbiotic relationship between the intestinal commensal microflora and the mucosal immune system.
Yi Yang, Lanmengxi Yang, Yilin Yang, Haiyi Deng, Shiyu Su, Yinxiao Xia, Jin Su, Yuheng Liu, Junwei Wu, Jing Zhang, Yao Liao, Lifu Wang   +11 more
wiley   +1 more source

Neurofilament, but not Alzheimer disease biomarkers in the acute phase correlate with cognitive performance after cardiac arrest. [PDF]

Resusc Plus
Lorentzson J, Lilja G, Blennow Nordström E, Blennow K, Zetterberg H, Hassager C, Wise MP, Benedet AL, Pellis T, Friberg H, Ashton N, Moseby Knappe M.   +11 more
europepmc   +1 more source

Amyloid-β vaccine for Alzheimer disease [PDF]

, 1999
Kristine Novak
openalex   +1 more source