Results 221 to 230 of about 9,708,599 (370)

Ecologically‐Valid Emotion Signatures Enhance Mood Disorder Diagnostics

Advanced Science, EarlyView.
This study identifies ecologically‐valid Divergent Emotional Functional Networks (DEFN), derived from dynamic functional connectivity during naturalistic movie watching. The DEFN reliably enhances diagnostic accuracy for mood disorders, including major depressive and bipolar disorders, demonstrating strong reproducibility across demographic factors and
Shuyue Xu, Linling Li, Ting Luo, Gan Huang, Li Zhang, Benjamin Becker, Zhen Liang   +6 more
wiley   +1 more source

Alzheimer Disease and Related Dementias in the Deaf Community: A Scoping Review. [PDF]

Public Health Rep
Lattimer TA, Tenzek KE, Ophir Y.
europepmc   +1 more source

Loss of neurons in the Nucleus basalis of Meynert in Parkinson disease with dementia, "Diffuse Lewy body disease" and senile dementia of alzheimer type.

, 1984
Masahiro Yoshimura, Hideo Mori, Masanori Tomonaga, Hiroshi Yamanouchi, Shigeki Kuzuhara   +4 more
openalex   +1 more source

Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes [PDF]

, 2007
Ang Li, Zhongcong Xie, Yuanlin Dong, K. Matthew McKay, Mary McKee, Rudolph E. Tanzi   +5 more
openalex   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

The GRK2 Overexpression Is a Primary Hallmark of Mitochondrial Lesions during Early Alzheimer Disease [PDF]

, 2009
Mark E. Obrenovich, Hector H. Palacios, Eldar Gasımov, Jerzy Leszek, Gjumrakch Aliev   +4 more
openalex   +1 more source

Regional age-related atrophy after screening for preclinical alzheimer disease

, 2021
Lauren N. Koenig, Pamela LaMontagne, Matthew F. Glasser, Randall J. Bateman, David M. Holtzman, Igor Yakushev, Jasmeer P. Chhatwal, Gregory S. Day, Clifford R. Jack, Catherine J. Mummery, Richard J. Perrin, Brian A. Gordon, John C. Morris, Joshua S. Shimony, Tammie L.S. Benzinger   +14 more
openalex   +2 more sources

Nanoscale Mapping of the Subcellular Glycosylation Landscape

Advanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter, Steffen Sass, Mike Heilemann, Thomas Kuner, Maja Klevanski   +4 more
wiley   +1 more source

TREM2 variants in Alzheimer\u27s disease [PDF]

, 2013
Benitez, Bruno, Cai, Yefei, Carrell, David, Cooper, Breanna, Cruchaga, Carlos, et al,, Goate, Alison, Morris, John C   +7 more
core   +1 more source

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

Alzheimer's & Dementia, 2011
R. Sperling, P. Aisen, L. Beckett, D. Bennett, S. Craft, A. Fagan, T. Iwatsubo, C. Jack, J. Kaye, T. Montine, Denise C. Park, E. Reiman, C. Rowe, E. Siemers, Y. Stern, K. Yaffe, M. Carrillo, B. Thies, M. Morrison‐Bogorad, M. Wagster, C. Phelps   +20 more
semanticscholar   +1 more source