Results 241 to 250 of about 5,368,097 (298)

Associations of Alzheimer Disease and Related Dementia Neuropathologies With Timely Diagnosis of Dementia in Healthcare Settings. [PDF]

Neurology
Chen Y, Chen A, Power MC, Grodstein F, Kapasi A, Capuano AW, Lange-Maia BS, Moghtaderi A, Stapp EK, Bhattacharyya J, Shah RC, Barnes LL, Bennett DA, James BD.   +13 more
europepmc   +1 more source

Cross‐Organ Multi‐Omics Profiling of Systemic Alterations in 5xFAD Mice and Changes Associated with Huanglian Jiedu Decoction Treatment

Advanced Science, EarlyView.
Cross‐organ multi‐omics reveals coordinated inflammatory and metabolic disturbances in 5xFAD mice. Huanglian Jiedu Decoction improves cognition and alleviates brain and liver abnormalities. Complementary hepatocyte–microglia conditioned‐medium experiments suggest PPAR‐γ involvement in treatment‐associated changes in microglial inflammation, providing ...
Wenya Gao, Jing Gao, Xiaohui Su, Xiangying Kong, Xiaolu Wei, Tunan Ding, Tiantian Guo, Shuangrong Gao, Yanyan Zhou, Junyi Zhou, Haiyu Zhao   +10 more
wiley   +1 more source

Blood Biomarkers of Alzheimer Disease and Rates of Global and Domain-Specific Cognitive Decline.

JAMA Netw Open
Laukka EJ, Ekström I, Valletta M, Winblad B, Fredolini C, Andersson S, Fratiglioni L, Vetrano DL, Grande G.   +8 more
europepmc   +1 more source

EOAD-Signature Atrophy Predicts Dementia in Early-Onset MCI due to Alzheimer Disease: An MRI-Based Prognostic Biomarker. [PDF]

Neurology
Paranhos T, Katsumi Y, Brickhouse MJ, Eloyan A, Eckbo R, Zaitsev A, Du A, La Joie R, Thangarajah M, Taurone A, Vemuri P, Jack CR, as the LEADS Consortium, Hammers DB, Aisen PS, Beckett LA, Koeppe R, Kukull WA, Toga AW, Atri A, Clark DG, Day GS, Duara R, Graff-Radford NR, Grant IM, Honig LS, Johnson E, Jones DT, Masdeu JC, Mendez MF, Musiek ES, Onyike CU, Riddle M, Rogalski E, Salloway S, Sha SJ, Turner RS, Wingo T, Wolk DA, Womack KB, Carrillo MC, Rabinovici GD, Apostolova LG, Dickerson BC, Eldaief MC, Touroutoglou A.   +45 more
europepmc   +1 more source

CircFAM65A/CANX Condensates Sequester FAM134B to Inhibit ER‐phagy and Suppress Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
The novel circRNA circFAM65A suppresses HCC progression. Mechanistically, circFAM65A drives CANX phase separation, which recruits FAM134B into condensates and blocks its interaction with LC3, thereby inhibiting ER‐phagy and HCC progression. Importantly, targeted circFAM65A delivery represents a potential therapeutic strategy for HCC.
Wenxiu Ru, Lunbiao Gan, Yu Lu, Yujing Guo, Qian Huang, Sha Yin, Fengze Nie, Sijia Di, Jiaqi Ning, Siyu Yao, Huanhuan Wan, Le Liu, Zehua Liu, Fa Yang, Weijun Qin, Weihong Wen   +15 more
wiley   +1 more source

Plasma eMTBR-tau243 and %p-tau217 for Biological Staging of Alzheimer Disease.

JAMA Neurol
Salvadó G, Horie K, Barthélemy NR, Schindler SE, Janelidze S, Orduña Dolado A, Bali D, Perrin RJ, Morris JC, Benzinger TLS, Gordon BA, Stomrud E, Mattsson-Carlgren N, Palmqvist S, Vogel JW, Bateman RJ, Ossenkoppele R, Hansson O.   +17 more
europepmc   +1 more source

Study on diagnostic genes and immune microenvironment disorder in comorbid atherosclerosis and Alzheimer disease. [PDF]

Medicine (Baltimore)
Ni P, Zhao B, Xv H.
europepmc   +1 more source

Salivary Cortisol and Cognitive Decline and Alzheimer Disease in Older Adults.

JAMA Netw Open
Ng TKS, Beck T, Sudhini Y, Wilson RS, Evans DA, Rajan KB.   +5 more
europepmc   +1 more source

Why it should be "Alzheimer disease" rather than "Alzheimer's disease". [PDF]

Free Neuropathol
Aguero C, Klein CZ, Haase G.
europepmc   +1 more source