Results 221 to 230 of about 362,575 (339)

Methylglyoxal Accumulation is Associated with Brain Inflammation after Myocardial Infarction with Sex and Regional Differences

Advanced Science, EarlyView.
This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley   +1 more source

Longitudinal Associations of Multimodal Core 1 Alzheimer Disease Biomarkers With Cognition in Aging and Preclinical Alzheimer Disease. [PDF]

Neurology
López-Martos D, Suárez-Calvet M, Milà-Alomà M, Gispert JD, Salvadó G, Brugulat-Serrat A, Shekari M, Minguillon C, Zetterberg H, Blennow K, Grau-Rivera O, Sánchez-Benavides G, ALFA study.   +12 more
europepmc   +1 more source

Spatially conserved pathoprotein profiling in the human suprachiasmatic nucleus in progressive Alzheimer disease stages [PDF]

Gowoon Son, Mihovil Mladinov, Felipe Luiz Pereira, Song Hua Li, Chia‐Ling Tu, Grace Judge, Yumi Yang, Cláudia Kimie Suemoto, Renata Elaine Paraízo Leite, Vítor Ribeiro Paes, Carlos Augusto Pasqualucci, Wilson Jacob Filho, Salvatore Spina, William W. Seeley, Wenhan Chang, Thomas C. Neylan, Lea T. Grinberg   +16 more
openalex   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Causality between noise pollution and Alzheimer disease: A Mendelian randomization analysis. [PDF]

Medicine (Baltimore)
Chen ZH, Wang LX, Li R, Jiang YH, Zong GH, Yi ZX, Ren XY, Jia BH.   +7 more
europepmc   +1 more source

Somatostatin, tau, and B-amyloid within the anterior olfactory nucleus in alzheimer disease

, 2010
Ricardo Insausti, Carlos de la Rosa Prieto, Alino José Martínez Marcos, Lucia Argandoña Palacios, Susana Garcia Muñozguren, Isabel María Úbeda Bañón, Daniel Saiz Sánchez   +6 more
openalex   +1 more source

Self‐Assisted Charge Storage‐Release Mechanism Enabling Flexible Design of Biomimetic Triboelectric Nanogenerators

Advanced Science, EarlyView.
Inspired by the mimosa, this study develops a flexible triboelectric nanogenerator with a novel microneedle array and battery‐mimetic architecture. The device introduces a spontaneous charge self‐regulation mechanism that confines the electric field below the air breakdown threshold, and achieves an outstanding charge density of 396.50 µC m−2 ...
Hanpeng Gao, Yamin Hu, Li Li, Ana Sofia Oliveira Henriques Moita, Xi Wang, Zong Meng, Zhiwu Han, Yan Liu   +7 more
wiley   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Deep convolutional neural networks for segmenting 3D in vivo multiphoton images of vasculature in Alzheimer disease mouse models

, 2019
Mohammad Haft‐Javaherian, Linjing Fang, Victorine Muse, Chris B. Schaffer, Nozomi Nishimura, Mert R. Sabuncu   +5 more
openalex   +2 more sources

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source