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The Lancet, 2016
Although the prevalence of dementia continues to increase worldwide, incidence in the western world might have decreased as a result of better vascular care and improved brain health. Alzheimer's disease, the most prevalent cause of dementia, is still defined by the combined presence of amyloid and tau, but researchers are gradually moving away from ...
Gholamreza Azizi, Abbas Mirshafiey
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Although the prevalence of dementia continues to increase worldwide, incidence in the western world might have decreased as a result of better vascular care and improved brain health. Alzheimer's disease, the most prevalent cause of dementia, is still defined by the combined presence of amyloid and tau, but researchers are gradually moving away from ...
Gholamreza Azizi, Abbas Mirshafiey
openaire +6 more sources
Comprehensive Therapy, 2007
Alzheimer's disease is the most prevalent form of dementia. There are significant efforts underway to elucidate the pathogenesis of this disease and to find ways to lessen the impact of the symptoms. This paper summarizes current knowledge regarding the diagnosis and treatment of the disorder.
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Alzheimer's disease is the most prevalent form of dementia. There are significant efforts underway to elucidate the pathogenesis of this disease and to find ways to lessen the impact of the symptoms. This paper summarizes current knowledge regarding the diagnosis and treatment of the disorder.
openaire +2 more sources
BMJ, 2009
Alzheimer’s disease and senile dementia are considered primary degenerative disorders of the brain. The delimitation of the two disorders is their onset: whether it is before or after the age of 65 years. As the neuropathological findings in the two disorders are similar they sometimes are sampled together.
Burns, Alistair; id_orcid 0000-0002-9837-0645 +1 more
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Alzheimer’s disease and senile dementia are considered primary degenerative disorders of the brain. The delimitation of the two disorders is their onset: whether it is before or after the age of 65 years. As the neuropathological findings in the two disorders are similar they sometimes are sampled together.
Burns, Alistair; id_orcid 0000-0002-9837-0645 +1 more
openaire +4 more sources
The Lancet, 2019
Alzheimer's disease (AD) dementia refers to a particular onset and course of cognitive and functional decline associated with age together with a particular neuropathology. It was first described by Alois Alzheimer in 1906 about a patient whom he first encountered in 1901.
Jose A, Soria Lopez +2 more
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Alzheimer's disease (AD) dementia refers to a particular onset and course of cognitive and functional decline associated with age together with a particular neuropathology. It was first described by Alois Alzheimer in 1906 about a patient whom he first encountered in 1901.
Jose A, Soria Lopez +2 more
openaire +4 more sources
Continuum, 2022
Alzheimer disease (AD) is the most common cause of dementia in adults (mid to late life), highlighting the importance of understanding the risk factors, clinical manifestations, and recent developments in diagnostic testing and therapeutics.Advances in fluid (CSF and blood-based) and imaging biomarkers are allowing for a more precise and earlier ...
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Alzheimer disease (AD) is the most common cause of dementia in adults (mid to late life), highlighting the importance of understanding the risk factors, clinical manifestations, and recent developments in diagnostic testing and therapeutics.Advances in fluid (CSF and blood-based) and imaging biomarkers are allowing for a more precise and earlier ...
openaire +2 more sources
Current Opinion in Neurobiology, 1996
Our understanding of the etiologies of the Alzheimer diseases is advancing rapidly, led by the discovery of relevant genetic mutations for autosomal-dominant forms of the disease and widespread confirmation of the role played by apolipoprotein E, the major susceptibility gene for the common form of Alzheimer's disease.
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Our understanding of the etiologies of the Alzheimer diseases is advancing rapidly, led by the discovery of relevant genetic mutations for autosomal-dominant forms of the disease and widespread confirmation of the role played by apolipoprotein E, the major susceptibility gene for the common form of Alzheimer's disease.
openaire +2 more sources
Lecanemab in Early Alzheimer’s Disease
New England Journal of Medicine, 2023Michio Kanekiyo +2 more
exaly
Donanemab in Early Alzheimer’s Disease
New England Journal of Medicine, 2021Liana Apostolova +2 more
exaly