Results 51 to 60 of about 1,307,128 (249)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

A latinidade do conceito de América Latina

Revista Geographia, 2013
De uma maneira geral, assumimos de modo tão naturalizado as designações e os recortes geográficos das regiões que visualizamos em mapas ou que utilizamos como referência de pertencimento e localização, que dificilmente nos questionamos sobre os processos
Pedro de Araújo Quental
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

El pícaro sigue al conquistador: Pablos surca los océanos

Revista de Literatura, 2009
Al final de sus aventuras Pablos, el protagonista del Buscón quevediano, prepara su huida a América, e informa al lector que en el Nuevo Mundo no cambió ni su suerte ni su estatus social o económico.
Victoriano Roncero López
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Azúcar en América

Revista de Indias, 2005
Este artículo, un ensayo introductorio del número monográfico de la «Revista de Indias» sobre la industria azucarera en América, revisa brevemente los rasgos fundamentales de las investigaciones acerca de ella y la razón por la que se ha convertido con ...
Antonio Santamaría García, Alejandro García Álvarez   +1 more
doaj   +1 more source

LA GESTIÓN INTEGRAL DE RESIDUOS SÓLIDOS URBANOS EN AMÉRICA LATINA

, 2023
Annie Lopez-Yamunaqué, José Iannacone‍   +1 more
openalex   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

El legado de la Real Expedición Filantrópica de la Vacuna (1803-1810): las juntas de vacuna

Asclepio: Revista de Historia de la Medicina y de la Ciencia, 2004
La Expedición de la Vacuna, dirigida por los médicos Francisco Xavier Balmis y José Salvany, es la gesta científica y sanitaria más importante de época colonial.
Susana María Ramírez Martín
doaj   +1 more source