Results 51 to 60 of about 3,047,347 (315)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Sacralización de la figura heroica de Francisco Morazán en América Central (1842-1942)
Mélanges de la Casa Velázquez : 46, 2, 2016, 2016 Cet article s’intéresse au processus de sacralisation de la figure héroïque de Francisco Morazán, président libéral hondurien de la République Fédérale d’Amérique Centrale pendant la décennie de 1830. Trois aspects sont abordés depuis sa mort en 1842 jusqu’au centenaire de celle-ci en 1942 : l’élaboration d’une structure narrative en prenant la figure ...
openaire +2 more sources
Desbordar el vacío siempre lleno de Vicens [PDF]
, 2016 Reseña del libro Maricruz Castro y Aline Pettersson (eds.), Josefina Vicens. Un vacío siempre lleno, Col.
Luna Martínez, María América +1 more
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Inicios de la misión en América: Isabel La Católica, Colón y Boil
Hispania Sacra, 2001 Análisis del inicio del cristianismo en América, refiriendo la construcción de los primeros templos en los años del descubrimiento y las primeras exploraciones del Nuevo Mundo.
Juan B. Olaechea Labayen
doaj +1 more source
La articulación conceptual entre contar-medir y discreto-continuo [PDF]
, 2010 En la enseñanza de las matemáticas a nivel medio superior y superior se tratan temas en los que se enfatiza la variación continua, sin relacionarse generalmente con una variación de tipo discreto, es decir, se presenta una dicotomía entre saberes ...
Fuentes, América +2 more
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YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Africa in America, for the English teaching at the University
Revista MENDIVE, 2022 The African culture is an intrinsic part of the culture in America, understood as a continent, and not only as the United States of America. It is expressed in language, art, music, dance, literature, history, etc. The exclusion of the African culture in
Rodolfo Acosta Padrón +2 more
doaj