Results 51 to 60 of about 5,910,398 (387)

Comunidad de práctica en derechos humanos y constitucionalismo transformador en América Latina

open access: yesAnuario de Derechos Humanos, 2020
En los últimos años, se ha venido desarrollando en América Latina una especie de derecho común de los derechos humanos, lo que entendemos como ius constitutionale commune. En el centro del surgimiento de este régimen se encuentran la Comisión Interamericana (CIDH) y la Corte Interamericana de Derechos Humanos (Corte IDH).
von Bogdandy, Armin, Urueña, René
openaire   +4 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Polarized America: The Dance of Ideology and Unequal Riches

open access: yes, 2006
The idea of America as politically polarized—that there is an unbridgeable divide between right and left, red and blue states—has become a cliche.
N. McCarty, K. Poole, H. Rosenthal
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Reparos en la censura de libros de tema americano en el siglo XVIII español: la Real Academia de la Historia y el Consejo de Indias

open access: yesCuadernos de Ilustración y Romanticismo, 2022
El artículo estudia la censura gubernativa de libros de tema indiano en el siglo XVIII español mediante un análisis comparativo de los expedientes informados por la Real Academia de la Historia y el Consejo de Indias.
Eduardo San José Vázquez
doaj   +1 more source

Chozos con techumbre de "castañuela" [PDF]

open access: yes, 1995
En número dedicado a ...
Jiménez Hernández, América
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

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