Results 61 to 70 of about 3,047,347 (315)

Humanismo clasicista mediterráneo y concepción antropológica del mundo: el caso de los jesuitas

Hispania, 1996
Se propone por el autor una reconsideración del papel de los jesuitas en la historia científica de la España Moderna, con énfasis principal en su contribución lingüística y etnográfica.
Fermín del Pino
doaj   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Científicos americanos en las cortes constituyentes. La cuestión ultramarina

Revista de Indias, 2003
Con este estudio pretendemos contribuir al mayor conocimiento sobre un capítulo poco estudiado de la historia de la ciencia hispanoamericana. Lo haremos a través del seguimiento de las actuaciones como diputados en las Cortes españolas de tres destacados
Jose Luis Maldonado Polo
doaj   +1 more source

WETWALL - an innovative design concept for the treatment of wastewater at an urban scale [PDF]

, 2018
Rising temperatures, increasing food demand and scarcity of water and land resources highlight the importance of promoting the sustainable expansion of agriculture to our urban environment, while preserving water resources.
Arias, Carlos Alberto, Bosch González, Montse, Carvalho, Pedro, Castellar da Cunha, Joana América, Farreras, Jordi, Montserrat Canals, Joan, Pérez Luque, Gabriel, Rysulova, Martina   +7 more
core   +4 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

«Como antiguas estatuas de bronce» Sobre la disolución del clasicismo en la relación histórica de un viaje a las regiones equinocciales del nuevo mundo, de Alejandro de Humboldt

Revista de Indias, 2001
La interpretación de América usando motivos clasicistas como modelos imperiales de apropiación, «antiquización», es una de las principales estrategias retóricas en los relatos de viajes de Alejandro de Humboldt.
Oliver Lubrich
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Pandemia-sindemia de la Covid-19 en América al 30/08/2023

Tecnología en Marcha
El presente estudio describe la evolución de la pandemia-sindemia de la Covid-19 en América al 30/08/2023, el cual cubre desde la declaración de la pandemia por parte de la OMS el 11/03/2020, la declaración del fin de la emergencia sanitaria al 06/05 ...
Darner Mora Alvarado
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source