Results 61 to 70 of about 134,596 (256)

Sacralización de la figura heroica de Francisco Morazán en América Central (1842-1942)

Mélanges de la Casa Velázquez : 46, 2, 2016, 2016
Cet article s’intéresse au processus de sacralisation de la figure héroïque de Francisco Morazán, président libéral hondurien de la République Fédérale d’Amérique Centrale pendant la décennie de 1830. Trois aspects sont abordés depuis sa mort en 1842 jusqu’au centenaire de celle-ci en 1942 : l’élaboration d’une structure narrative en prenant la figure ...
openaire   +2 more sources

Memoria 1998-1999

, 1999
En esta memoria se reflejan los aspectos más relevantes de los programas de la Universidad Especializada de las Américas, sobre todo aquellas acciones realizadas en las unidades académicas, de investigación , extensión, servicio y apoyo administrativo ...
Universidad Especializada de las Américas, UDELAS
core   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Memoria 2009

, 2010
La Universidad Especializada de las Américas -UDELAS- acatando lo dispuesto en la Constitución Nacional, presenta este informe que identifica las mejoras y apertura de nuevas carreras mediante el enfoque interdisciplinario y de pariticipación ciudadana ...
Universidad Especializada de las Américas, UDELAS
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Alertas sanitarias de productos médicos subestándares, falsificados y no registrados al inicio de la pandemia de COVID-19 en las Américas

Revista Panamericana de Salud Pública
Objetivo. Identificar y analizar los incidentes de productos médicos subestándares, falsificados, no registrados y robados al inicio de la pandemia de COVID-19. Métodos. Búsqueda detallada en los sitios web de las autoridades reguladoras de las Américas.
Marisa Gorordo, Robin Rojas-Cortés, Jesica Carino, Juanita Vahos Zambrano, José Luis Castro   +4 more
doaj   +1 more source

O avanço internacional da regulação da cannabis e o injustificável atraso brasileiro

Boletim IBCCRIM, 2023
Há 10 anos o mundo presencia uma enorme transformação em termos de política de drogas. Diversos países e unidades federativas têm flexibilizado as restrições para o uso industrial, medicinal e mesmo recreativo da cannabis.
Dr. Paulo José dos Reis Pereira
doaj