Results 71 to 80 of about 317,652 (262)
Revista Panamericana de Salud PúblicaObjetivo. Identificar y analizar los incidentes de productos médicos subestándares, falsificados, no registrados y robados al inicio de la pandemia de COVID-19. Métodos. Búsqueda detallada en los sitios web de las autoridades reguladoras de las Américas.
Marisa Gorordo +4 more
doaj +1 more source
O avanço internacional da regulação da cannabis e o injustificável atraso brasileiro
Boletim IBCCRIM, 2023 Há 10 anos o mundo presencia uma enorme transformação em termos de política de drogas. Diversos países e unidades federativas têm flexibilizado as restrições para o uso industrial, medicinal e mesmo recreativo da cannabis.
Dr. Paulo José dos Reis Pereira
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Super-spreading Events and Contribution to Transmission of MERS, SARS, and COVID-19 [PDF]
, 2020 There is no clear definition for the term ‘super-spreader’ or ‘super-spreading event’. The World Health Organization refers to a super-spreader as a patient (or an event) that may transmit infection to a larger number of individuals than is usual by one ...
Al-Tawfiq, Jaffar A. +1 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
COVID-19 vaccine equity in the Americas
The Lancet Regional Health. Americas, 2022 The Lancet Regional Health– Americas
doaj +1 more source
Las Américas y el Mundo 2008 [PDF]
, 2009 El objetivo central de este estudio es llenar un vacío de información empírica en un área estratégica para la región, donde los datos independientes y confiables son escasos.
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Borders Manifest: Racializing the Nicaraguan Refugee in Costa Rica [PDF]
, 2019 I look to border responses of North American countries as refugees and migrants move across them to argue that border responses racialize the foreign other in receiving countries.
Twidwell, Theodore B.
core +1 more source