Results 71 to 80 of about 159,730 (246)

O avanço internacional da regulação da cannabis e o injustificável atraso brasileiro

open access: yesBoletim IBCCRIM, 2023
Há 10 anos o mundo presencia uma enorme transformação em termos de política de drogas. Diversos países e unidades federativas têm flexibilizado as restrições para o uso industrial, medicinal e mesmo recreativo da cannabis.
Dr. Paulo José dos Reis Pereira
doaj  

Tendencias evolutivas de las políticas de seguridad y defensa en las Américas

open access: yes, 2022
The book is a collective effort to understand where the discussion on the security of societies in the Americas is heading. To do so, the authors took different case studies, achieving a nuanced perspective of the discussion in the Hemisphere.
Santamaría-Clavijo, Jorge Enrique   +25 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Informe estadístico Primer Semestre 2020 [PDF]

open access: yes, 2020
El documento presenta un compendio de la estadística de la Universidad Especializada de las Américas, durante el Primer semestre del 2020. Incluye datos de la matrícula, por sexo, edad desde la sede, extensiones y programas académicos.
Universidad Especializada de las Américas
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

COVID-19 vaccine equity in the Americas

open access: yesThe Lancet Regional Health. Americas, 2022
The Lancet Regional Health– Americas
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Acuerdo No. 005-2008 (de 23 de enero de 2008) "Por el cual se se aprueba el informe de codificación y recodificación de asignaturas"

open access: yes, 2008
El documento presenta el acuerdo académico aprobado el 23 de enero de 2008 en la Universidad Especializada de las Américas, sobre la codificación y re codificación de asignaturas de las diferentes ...
Universidad Especializada de las Américas
core   +1 more source

Fortalecimiento del liderazgo para la gestión educativa en las Américas: una estrategia de investigación-acción

open access: yesRevista Panamericana de Salud Pública
La formación de recursos humanos en salud es una preocupación recurrente. El Campus Virtual de Salud Pública (CVSP) es la plataforma educativa de la Organización Panamericana de Salud (OPS) que busca mejorar la accesibilidad a la educación en salud ...
Gabriel Listovsky   +10 more
doaj   +1 more source

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