Results 91 to 100 of about 20,302 (212)

Ptf1a is expressed transiently in all types of amacrine cells in the embryonic zebrafish retina [PDF]

, 2009
BACKGROUND: The vertebrate retina is composed of five major types of neurons: three excitatory (photoreceptors, bipolar cells and ganglion cells) and two inhibitory (horizontal and amacrine cells).
Patricia R Jusuf, William A Harris
core   +1 more source

Dynamic Retinal Pathology in Glaucoma Progression Revealed by High‐Resolution Functional Imaging In Vivo

Laser &Photonics Reviews, Volume 20, Issue 5, 6 March 2026.
In this work, we investigated the dynamic retinal pathology of glaucoma from onset to late stages through longitudinal in vivo high‐resolution imaging in a silicone oil‐induced ocular hypertension (SOHU) glaucoma mouse model. We developed an optimized adaptive optics two‐photon excitation fluorescence microscopy (AO‐TPEFM) technique for morphological ...
Yiming Fu, Pham Binh Minh, Sicong He, Yingzhu He, Zhongya Qin, Ting Xie, Jianan Qu   +6 more
wiley   +1 more source

A Nonlinear Model of Spatiotemporal Retinal Processing: Simulations of X and Y Retinal Ganglion Cell Behavior [PDF]

, 1993
This article describes a nonlinear model of neural processing in the vertebrate retina, comprising model photoreceptors, model push-pull bipolar cells, and model ganglion cells.
Gaudiano, Paolo
core   +1 more source

Neuroinflammation‐Associated Optic Structural–Functional Degeneration in Early Diabetic Optic Neuropathy

Journal of Diabetes, Volume 18, Issue 3, March 2026.
OCT imaging assessments and visual tests, which were validated by pyroptosis of retinal ganglion cells (RGC) and upregulation of NLRP3 and GSDMD expression, established an early structure‐function‐pathology diabetic optic neuropathy (DON) model in high glucose & obesity mice. Early retinal nerve fiber layer (RNFL)/total retinal thickness (TRT) thinning
Jingyuan Zhu, Jinyuan Wang, Haihan Zhang, Mingyang Wang   +3 more
wiley   +1 more source

Increased phosphorylation of Cx36 gap junctions in the AII amacrine cells of RD retina

Frontiers in Cellular Neuroscience, 2015
Retinal degeneration (RD) encompasses a family of diseases that lead to photoreceptor death and visual impairment. Visual decline due to photoreceptor cell loss is further compromised by emerging spontaneous hyperactivity in inner retinal cells.
Elena eIvanova, Christopher W Yee, Botir T Sagdullaev   +2 more
doaj   +1 more source

Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development

Frontiers in Molecular Neuroscience, 2018
During mammalian retinal development, the multipotent progenitors differentiate into all classes of retinal cells under the delicate control of transcriptional factors.
Dongchang Xiao, Kangxin Jin, Kangxin Jin, Mengqing Xiang   +3 more
doaj   +1 more source

Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression. [PDF]

, 2020
Retinoblastoma is an aggressive childhood cancer of the developing retina that initiates by biallelic RB1 gene inactivation. Tumor progression in retinoblastoma is driven by epigenetics, as retinoblastoma genomes are stable, but the mechanism(s) that ...
Benavente, Claudia A, Gu, Yijun, Mehta, Aditi, Spitale, Robert C, Suh, Susie, Wang, Jingtian, Wu, Jie, Wu, Stephanie C, Zocchi, Loredana   +8 more
core  

The expression of irx7 in the inner nuclear layer of zebrafish retina is essential for a proper retinal development and lamination.

PLoS ONE, 2012
Irx7, a member in the zebrafish iroquois transcription factor (TF) family, has been shown to control brain patterning. During retinal development, irx7's expression was found to appear exclusively in the inner nuclear layer (INL) as soon as the ...
Yuqing Zhang, Yifan Yang, Caleb Trujillo, Wenxuan Zhong, Yuk Fai Leung   +4 more
doaj   +1 more source

A novel retinal oscillation mechanism in an autosomal dominant photoreceptor degeneration mouse model

Frontiers in Cellular Neuroscience, 2016
It has been shown in rd1 and rd10 models of photoreceptor degeneration (PD) that inner retinal neurons display spontaneous and rhythmic activities. Furthermore, the rhythmic activity has been shown to require the gap junction protein connexin 36, which ...
Hung-Ya eTu, Hung-Ya eTu, Hung-Ya eTu, Yu-Jiun eChen, Adam Rory McQuiston, Chuan-Chin eChiao, Chuan-Chin eChiao, Chuan-Chin eChiao, Ching-Kang eChen, Ching-Kang eChen, Ching-Kang eChen   +10 more
doaj   +1 more source

Nfia Is Critical for AII Amacrine Cell Production: Selective Bipolar Cell Dependencies and Diminished ERG. [PDF]

J Neurosci, 2023
Keeley PW, Trod S, Gamboa BN, Coffey PJ, Reese BE.   +4 more
europepmc   +1 more source