Results 31 to 40 of about 26,228 (200)
The effects of memantine on prepulse inhibition. [PDF]
, 2009 Reduced prepulse inhibition (PPI) of startle provides evidence of deficient sensorimotor gating in several disorders, including schizophrenia. The role of NMDA neurotransmission in the regulation of PPI is unclear, due to cross-species differences in the
Bergsma, F +4 more
core +2 more sources
Potential antidepressant effect of amantadine: a review of preclinical studies and clinical trials
Brazilian Journal of Psychiatry, 2018 Objective: Amantadine blocks N-methyl-D-aspartate (NMDA) receptors and has dopaminergic and noradrenergic action, a neurochemical profile that suggests its potential as an antidepressant drug.
Inara F. Raupp-Barcaro +3 more
doaj +1 more source
Pharmaceuticals, 2023 Blood-to-retina transport across the inner blood–retinal barrier (BRB) is a key determinant of retinal drug concentration and pharmacological effect. Recently, we reported on the amantadine-sensitive drug transport system, which is different from well ...
Yusuke Shinozaki +3 more
doaj +1 more source
Right ventricular outflow tract tachycardia after an initial dose of amantadine
Türk Kardiyoloji Derneği Arşivi, 2015 Amantadine hydrochloride is an antiviral agent that is also effective in the treatment of Parkinson's disease. In the literature, cardiac arrhythmia is reported in toxic doses of amantadine, but in this paper we report a patient with right ventricular ...
Cüneyt Kocaş +3 more
doaj +1 more source
Amantadine can induce intra-epithelial deposition in the cornea
American Journal of Ophthalmology Case Reports, 2020 Purpose: Amantadine has been reported to cause various corneal complications, such as superficial punctate keratitis, corneal endothelial dysfunction, and corneal edema.
Asayo Yoshinaka +2 more
doaj +1 more source
Preliminary Study of Intravenous Amantadine Treatment for Ataxia Management in Patients with Probable Multiple System Atrophy with Predominant Cerebellar Ataxia [PDF]
Journal of Movement Disorders, 2012 Background and Purpose: Multiple system atrophy with predominant cerebellar ataxia is a disabling neurologic disease. However, effective management has not yet been established.
Jinyoung Youn +3 more
doaj +1 more source
BMC Ophthalmology, 2022 Background To report a case of a patient showing bilateral corneal opacities after amantadine chronic treatment for Parkinson’s Disease (PD) and corneal edema associated with intra-epithelial and -endothelial depositions. After amantadine discontinuation
Michela Cennamo +4 more
doaj +1 more source
Amantadine in Treatment of Dysthymia—The Pilot Case Series Study
Pharmaceuticals, 2023 Dysthymia is a common chronic mood disorder in which isolated symptoms of depression persist for at least 2 years. Despite the many medications recommended for the treatment of dysthymia, no recommendations have yet been made for the treatment of ...
Marek Krzystanek +5 more
doaj +1 more source
Principles of appropriate antibiotic use for treatment of uncomplicated acute bronchitis: background. [PDF]
, 2001 The following principles of appropriate antibiotic use for adults with acute bronchitis apply to immunocompetent adults without complicating comorbid conditions, such as chronic lung or heart disease.
Bartlett, JG +7 more
core +2 more sources
Structural, Electronic, and Vibrational Properties of Amino-adamantane and Rimantadine Isomers
, 2010 We performed a first principles total energy investigation on the structural, electronic, and vibrational properties of adamantane molecules, functionalized with amine and ethanamine groups.
Assali, Lucy V. C. +3 more
core +1 more source