Results 51 to 60 of about 358 (125)
Immunohistochemical stainings of GEP100 (A), AMAP1 (B), EGFR (C) and HER2 (D).
, 2013 Representative figures are shown. Bars, 100 µm. EGFR: epidermal growth factor receptor. HER2: human epidermal growth factor receptor 2.
Haruka Handa (343721) +15 more
core +1 more source
The efficiency of cationic-based hydrogels in heavy metal removal from wastewater
The present study draws attention to arsenic (V) (As(V)), chromium (III) (Cr(III)), and chromium (VI) (Cr(VI)) heavy metal pollutants, which have negative effects on aquatic ecosystems and indirectly pose a serious threat to the health of living things ...
Kalipa, Salieva +3 more
core +1 more source
Characterization of antibiotic-resistance traits in Akkermansia muciniphila strains of human origin. [PDF]
Sci Rep, 2022 Filardi R, Gargari G, Mora D, Arioli S.
europepmc +1 more source
Orchestration of mesenchymal plasticity and immune evasiveness via rewiring of the metabolic program in pancreatic ductal adenocarcinoma. [PDF]
Front Oncol, 2022 Hashimoto A +3 more
europepmc +1 more source
EMT-driven cancer malignancy: what is the fundamental matter?
, 2019 配架番号：2475Despite global intellectual efforts that have continued for over half a century, cancer is still an incurable disease. There are two main reasons for this difficulty; treatment resistance and metastatic recurrence.
半田, 悠
core
Dual roles of AMAP1 in the transcriptional regulation and intracellular trafficking of carbonic anhydrase IXBackground: The cell-surface enzyme carbonic anhydrase IX (CAIX/CA9) promotes tumor growth, survival, invasion, and metastasis, mainly via its pH-regulating functions. Owing to its tumor-specific expression, CAIXtargeting antibodies/chemicals are utilized for therapeutic and diagnostic purposes.
openaire +1 more source
, 2013 β2-Glycoprotein I (β2GPI)は、主に凝固線溶系における制御因子として解析されてきた。この分子はplasmin産生が亢進している状態下ではnicked formとして存在する。我々はこれまでにβ2GPIおよびnicked β2GPIが血管新生抑制物質であることを報告した。本研究ではVEGFR2の下流に存在し、腫瘍転移に重要な細胞内シグナル伝達経路GEP100-Arf6-AMAP1に対するβ2GPI、nicked β2GPIの制御能を評価し、腫瘍転移抑制分子としての機能を解析した ...
60272431, 1321, 宮崎, 忠昭
core
High expression of AMAP1, an ARF6 effector, is associated with elevated levels of PD-L1 and fibrosis of pancreatic cancerBackground Not merely the onset of immune evasion, but other factors, such as acidosis and fibrosis, are also major barriers in cancer therapeutics. Dense fibrosis is a hallmark of pancreatic ductal carcinoma (PDAC), in which hyperactivation of focal adhesion kinase (FAK) in tumor cells was shown to be crucial.
openaire +1 more source
Effects of the Mutant TP53 Reactivator APR-246 on Therapeutic Sensitivity of Pancreatic Cancer Cells in the Presence and Absence of WT-TP53. [PDF]
Cells, 2022 Abrams SL +14 more
europepmc +1 more source
AMAP1 オ カイシタ ニュウガン サイボウ ノ シンジュン カテイ ニ オケル Cb1 ケツゴウ タンパクシツ CIN85 ノ カンヨ
, 2007 京都大学0048新制・課程博士博士(生命科学)甲第13244号生博第114号新制||生||17(附属図書館)UT51-2007-H517京都大学大学院生命科学研究科高次生命科学専攻(主査)教授 佐邊 壽孝, 教授 竹市 雅俊, 教授 米原 伸学位規則第4条第1項該当Doctor of Life ScienceKyoto ...
南, 璡旻
core