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Cell cycle modulatory effects of Amaryllidaceae alkaloids
Life Sciences, 2018The birth, growth, proliferation and death of cells involve a rigorous and continuous process in place to ensure the survival of living organisms. The cell cycle prevails at the core of this process to facilitate the division of a parent cell as well as the duplication of its genetic matter. Although checkpoints exist to steer the course of a cell from
Jerald J. Nair, Johannes van Staden
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A Synthesis of the Amaryllidaceae Alkaloid Pratosine
Journal of Natural Products, 1996A synthesis of pratosine by thermolysis of the Michael adduct obtained from 5-hydroxy-8,9-dimethoxy-6(5H)-phenanthridone and methyl propiolate is described.
M M, Pereira, S, Prabhakar, A M, Lobo
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Acetylcholinesterase Enzyme Inhibitory Effects of Amaryllidaceae Alkaloids
Planta Medica, 2004Twenty-three Amaryllidaceae alkaloids having several different ring types were evaluated for their acetylcholinesterase enzyme (AChE) inhibitory activity. The alkaloid 1- O-acetyllycorine (IC50 : 0.96 +/- 0.04) showed significant AChE inhibitory activity.
Esameldin E, Elgorashi +2 more
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Alkaloids from Hippeastrum morelianum Lem. (Amaryllidaceae)
Magnetic Resonance in Chemistry, 2011AbstractThe Amaryllidaceae family has proven to be a rich source of active molecules. As part of an ongoing project, we report a phytochemical study of Hippeastrum morelianum (Amaryllidaceae), from which we have isolated two homolycorine‐type alkaloids, the new 2α,7‐dimethoxyhomolycorine (1) and the poorly described candimine (2), as well as six known ...
Raquel B, Giordani +7 more
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Alkaloids and triterpenoids from Ammocharis coranica (Amaryllidaceae)
Phytochemistry, 2000The bulbs of Ammocharis coranica yielded eight alkaloids: lycorine, acetylcaranine and crinamine, which have been reported previously from A. coranica, 1-O-acetyllycorine, hippadine, 6 alpha-hydroxypowelline and hamayne, which have been reported from other members of the Amaryllidaceae, 1-O-acetyl-9-O-demethylpuviine, which has not been described ...
N, Koorbanally +2 more
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Amaryllidaceae Alkaloids and Colchicine
1968About one hundred alkaloids are known from the family Amaryllidaceae. In their route of biosynthesis they bear several resemblances to the morphine alkaloids. In each type there are two six-membered rings derived from aromatic amino acids; and the additional ring closures are apparently produced by a mechanism of phenolate free radical coupling.
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[Amaryllidaceae alkaloids from Lycoris radiata].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2019Three aporphine-type alkaloids (1-3), three lycorine-type alkaloids (4-6), two crinane type alkaloids (7, 8) and one phenanthridine-type alkaloid (9) were isolated from the chloroform soluble fraction of 70% ethanol extract of the bulbs of Lycoris radiata through various column chromatographies over silica gel, ODS, Sephadex LH-20 and MCI.
Jiang, Hu +9 more
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