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Amaryllidaceae and Sceletium alkaloids
Natural Product Reports, 2003The latest progress on the isolation, identification, biological activity and synthetic studies of the structurally diverse alkaloids from plants of family Amaryllidaceae has been summarized in this review.
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Cytotoxic Activity of Amaryllidaceae Alkaloids
Planta Medica, 199525 Amaryllidaceae alkaloids belonging to different skeletal types were evaluated for their cytotoxic activity against one murine non-tumoral cell line (LMTK) and two human tumoral cell lines (Molt4 and HepG2) according to established protocols. Significant differences of activity related with the type of skeleton of the tested alkaloids could be ...
B, Weniger +7 more
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Total Synthesis of Amaryllidaceae Alkaloid Buflavine
The Journal of Organic Chemistry, 2002A concise synthesis of the amaryllidaceae alkaloid buflavine (1) and its regioisomer (2) involving sequential Meyers' biaryl coupling, enecarbamate formation, and hydrogenation followed by ultimate intramolecular reductive amination is presented.
Christophe, Hoarau +3 more
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Apoptosis-Inducing Effects of Amaryllidaceae Alkaloids
Current Medicinal Chemistry, 2016The Amaryllidaceae occupies a privileged status amongst medicinal plants in having delivered the Alzheimer's drug galanthamine to the clinical market. Following its resounding success, there have been several positive indicators for the emergence of an anticancer drug from the family due to the potent antiproliferative activities manifested by several ...
Jerald J, Nair +2 more
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Alkaloid N-oxides of amaryllidaceae
Phytochemistry, 1988Ungiminorine N-oxide was isolated from Pancratium maritimum, and homolycorine N-oxide and O-methyl lycorenine N-oxide from Lapiedra martinezii. These compounds represent the first examples of naturally occurring N-oxides from the Amaryllidaceae. © 1988.
R. Suau +5 more
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Heterocyclic Amaryllidaceae Alkaloids: Biosynthesis and Pharmacological Applications
Current Topics in Medicinal Chemistry, 2016Amaryllidaceae alkaloids (AAs), which are natural heterocyclic compounds, are isolated from Amaryllidaceae plants such as narcissus, snowdrop and spider lily. AAs have been extensively studied due to their multiple pharmacological properties. Nevertheless, knowledge of AA synthesis in plants is lacking and most genes encoding enzymes involved in their ...
Tarun, Hotchandani +1 more
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Chemodiversity, chemotaxonomy and chemoecology of Amaryllidaceae alkaloids
2020The Amaryllidaceae alkaloids are a distinctive chemotaxonomic feature of the subfamily Amaryllidoideae of the family Amaryllidaceae, which consists of 59 genera and >800 species distributed primarily in tropical and subtropical areas. Since the first isolation, ca.
Berkov, Strahil +3 more
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Amaryllidaceae alkaloids: Absolute configuration and biological activity
Chirality, 2017AbstractPlants belonging to the Amaryllidaceae family are well known for their ornamental and medicinal use. Plant members of this group are distributed through both tropical and subtropical regions of the world and are dominant in Andean South America, the Mediterranean basin, and southern Africa.
Alessio Cimmino +4 more
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ChemInform Abstract: The Amaryllidaceae Alkaloids
ChemInform, 1998AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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Four new Amaryllidaceae alkaloids from Zephyranthes candida
Journal of Natural Medicines, 2014Four new Amaryllidaceae alkaloids (1-4) possessing a homolycorine-type or a crinine-type skeleton have been isolated from the aerial part of Zephyranthes candida, and their structures were elucidated on the basis of spectroscopic data. The stereochemistry was elucidated by combination of NOESY correlations and CD analyses.
Nanase, Shitara +8 more
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