Results 151 to 160 of about 2,622 (201)
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A Synthesis of the Amaryllidaceae Alkaloid Pratosine
Journal of Natural Products, 1996A synthesis of pratosine by thermolysis of the Michael adduct obtained from 5-hydroxy-8,9-dimethoxy-6(5H)-phenanthridone and methyl propiolate is described.
M M, Pereira, S, Prabhakar, A M, Lobo
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Cytotoxic Activity of Amaryllidaceae Alkaloids
Planta Medica, 199525 Amaryllidaceae alkaloids belonging to different skeletal types were evaluated for their cytotoxic activity against one murine non-tumoral cell line (LMTK) and two human tumoral cell lines (Molt4 and HepG2) according to established protocols. Significant differences of activity related with the type of skeleton of the tested alkaloids could be ...
B, Weniger +7 more
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Amaryllidaceae andSceletiumalkaloids
Natural Product Reports, 2019Recent progress on the isolation, identification, biological activity and synthetic studies of Amaryllidaceae alkaloids, as well as the structurally close alkaloids from theSceletiumgenus, published from July 2015 to June 2017 are reviewed.
Zhong Jin, Guangmin Yao
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Amaryllidaceae and Sceletium alkaloids
Natural Product Reports, 2003The latest progress on the isolation, identification, biological activity and synthetic studies of the structurally diverse alkaloids from plants of family Amaryllidaceae has been summarized in this review.
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Total Synthesis of Amaryllidaceae Alkaloid Buflavine
The Journal of Organic Chemistry, 2002A concise synthesis of the amaryllidaceae alkaloid buflavine (1) and its regioisomer (2) involving sequential Meyers' biaryl coupling, enecarbamate formation, and hydrogenation followed by ultimate intramolecular reductive amination is presented.
Christophe, Hoarau +3 more
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Apoptosis-Inducing Effects of Amaryllidaceae Alkaloids
Current Medicinal Chemistry, 2016The Amaryllidaceae occupies a privileged status amongst medicinal plants in having delivered the Alzheimer's drug galanthamine to the clinical market. Following its resounding success, there have been several positive indicators for the emergence of an anticancer drug from the family due to the potent antiproliferative activities manifested by several ...
Jerald J, Nair +2 more
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Alkaloid N-oxides of amaryllidaceae
Phytochemistry, 1988Ungiminorine N-oxide was isolated from Pancratium maritimum, and homolycorine N-oxide and O-methyl lycorenine N-oxide from Lapiedra martinezii. These compounds represent the first examples of naturally occurring N-oxides from the Amaryllidaceae. © 1988.
R. Suau +5 more
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Synthesis of the amaryllidaceae alkaloid, lycorine
Journal of the Chemical Society, Chemical Communications, 1975A key intermediate for the total synthesis of lycorine has been prepared in racemic form; the optically pure form of this epoxylycorinane lactam, obtained from lycorine, has been reconverted into the alkaloid.
Yoshisuke Tsuda +9 more
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Amaryllidaceae Alkaloids and Colchicine
1968About one hundred alkaloids are known from the family Amaryllidaceae. In their route of biosynthesis they bear several resemblances to the morphine alkaloids. In each type there are two six-membered rings derived from aromatic amino acids; and the additional ring closures are apparently produced by a mechanism of phenolate free radical coupling.
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Cytotoxic Lycorine Alkaloids of the Plant Family Amaryllidaceae
Bioorganic ChemistryThe plant family Amaryllidaceae is embellished with a diverse array of antiproliferative alkaloid principles. Chief amongst these are the lycorine alkaloids, which have attracted considerable attention as potential anticancer drugs. This account tracks developments in the field with these substances encompassing the years 2015-2019.
Jerald J, Nair, Johannes, van Staden
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