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Toxins, 2019 Amatoxins (AMAs) are lethal toxins found in a variety of mushroom species. Detection methods are needed to determine the occurrence of AMAs in mushroom species suspected in mushroom poisonings.
Candace S Bever +2 more
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Comment on “N-acetylcysteine as a treatment for amatoxin poisoning”
Clinical Toxicology, 2020We would like to thank Liu and colleagues for their investigation into the benefit of N-acetylcysteine (NAC) as a treatment for cyclopeptide containing mushroom toxicity [1].
Nicholas J. Connors +2 more
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Scandinavian Journal of Urology and Nephrology, 1990
Ingestion of mushrooms followed after 6-12 hours by gastrointestinal symptoms and after 3-4 days by hepatic symptoms is diagnostic for the life-threatening amatoxin intoxication and should be treated as soon as possible. Four case histories are reported and recommendations for treatment are given.
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Ingestion of mushrooms followed after 6-12 hours by gastrointestinal symptoms and after 3-4 days by hepatic symptoms is diagnostic for the life-threatening amatoxin intoxication and should be treated as soon as possible. Four case histories are reported and recommendations for treatment are given.
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Toxicon, 1987
A novel approach for the production of [125I]amatoxin and anti-amanitin is described. The antigen and the starting material for Bolton Hunter iodination is prepared by periodic acid oxidation of the gamma-delta-dihydroxy-isoleucine side chain of alpha-amanitin followed by reductive amination. The antigen seems to be of low apparent toxicity.
R Y, Andres, W, Frei
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A novel approach for the production of [125I]amatoxin and anti-amanitin is described. The antigen and the starting material for Bolton Hunter iodination is prepared by periodic acid oxidation of the gamma-delta-dihydroxy-isoleucine side chain of alpha-amanitin followed by reductive amination. The antigen seems to be of low apparent toxicity.
R Y, Andres, W, Frei
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Amatoxins in wood-rottingGalerina marginata
Mycologia, 2004Amatoxins, bicyclic octapeptide derivatives responsible for severe hepatic failure, are present in several Basidiomycota species belonging to four genera, i.e. Amanita, Conocybe, Galerina and Lepiota. DNA studies for G. autumnalis, G. marginata, G. oregonensis, G. unicolor and G.
Enjalbert, Françoise +4 more
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Amatoxine und Knollenbl�tterpilzvergiftung
Naturwissenschaften, 1979Amatoxins are the sole cause of human Amanita poisoning, inhibition of transcription eventually leading to cell necrosis. The toxins are easily excreted into the bile fluid, a fact which postulates the interruption of the enterohepatic circulation. All therapeutic means should be applied in order to decrease the serum concentration of the toxins as ...
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Mushrooms, amatoxins and the liver
Journal of Hepatology, 2005Acute liver failure (ALF) due to mushrooms containing amatoxins is relatively rare. In a survey of ALF in Spain, only 10 out of 267 cases (4%) were caused by amatoxins (pending publication). Amatoxin poisoning is a world wide problem: 50–100 fatal cases are reported yearly in Western Europe, being less common in the United States with fewer than 100 ...
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