This review describes the features of grade C molar‐incisor pattern periodontitis and discusses the role of A. actinomycetemcomitans in its pathogenesis and why molars and incisors are preferably affected. Possible future studies on this aggressive disease in primary and permanent dentition and emerging omics techniques for diagnosis and management are
Luigi Nibali +3 more
wiley +1 more source
Summary of the IADR Cariology Research, Craniofacial Biology, and Mineralized Tissue Groups Symposium, Iguaçu Falls, Brazil, June 2012: Gene-environment Interactions and Epigenetics in Oral Diseases: Enamel Formation and its Clinical Impact on Tooth Defects, Caries, and Erosion. [PDF]
Characteristics of enamel may influence or modulate individual susceptibility to caries and erosion. These characteristics are defined during development, which is under strict genetic control, but can easily be modified in many ways by environmental ...
Gerlach, Raquel F +4 more
core +2 more sources
MDM2-Mediated p21 Proteasomal Degradation Promotes Fluoride Toxicity in Ameloblasts
Fluoride overexposure is an environmental health hazard and can cause enamel and skeletal fluorosis. Previously we demonstrated that fluoride increased acetylated-p53 and its downstream target p21 in ameloblast-derived LS8 cells. However, p21 function in
Huidan Deng +4 more
doaj +1 more source
Enamel malformations associated with a defined dentin sialophosphoprotein mutation in two families [PDF]
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90129/1/EOS_874_sm_FigS1-9.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/90129/2/j.1600-0722.2011.00874.x ...
Bai +51 more
core +1 more source
Inflammation and mechanical force‐induced bone remodeling
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon +6 more
wiley +1 more source
FAM20A variants cause AI1G, marked by enamel defects, gingival overgrowth and ectopic calcifications. RNA sequencing of patient‐derived gingival fibroblasts showed dysregulated genes in adhesion, proliferation and signalling pathways. Functional assays revealed increased cell proliferation, impaired ECM interactions and osteogenesis, suggesting FAM20A ...
Kanokwan Sriwattanapong +9 more
wiley +1 more source
Les phosphoprotéines sécrétées liant le calcium (SCPP) impliquées dans la formation de l'émail dentaire : expression chez le lézard Anolis carolinensis et évolution chez les amniotes [PDF]
Enamel formation requires the involvement of secretory calcium-binding phosphoproteins. Three of them, amelogenin (AMEL), ameloblastin (AMBN) and enamelin (ENAM), have been extensively studied in mammals.
Gasse, Barbara
core +2 more sources
Tooth attachment in vertebrates ranges from ligament‐based anchorage in mammals to direct fusion in many reptiles. In the veiled chameleon, we identified a transient cell population—termed ankyloblasts—at the tooth‐bone interface. These cells exhibit both odontoblast‐ and osteoblast‐like features.
M. Šulcová +11 more
wiley +1 more source
The so-called adenoameloblastoma. Report of a case [PDF]
A case of the so-called adenoameloblastoma developed in the right maxillary sinus of a 10-y-old girl was reported. The histological features of this tumor were discussed in detail.
Iwata, Katsumi
core +1 more source
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale +6 more
wiley +1 more source

