Results 31 to 40 of about 5,305 (247)
ODONTO: Dental Journal, 2020 Background: Tooth development during the embryonic period is a complex process that needs enough nutrition for the formation of healthy dental tissue. Kallikrein-related peptidase-4 (KLK-4) is a serine proteinase secreted by ameloblast during transition ...
Salma Samia +2 more
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An integrated gene regulatory network controls stem cell proliferation in teeth. [PDF]
, 2007 Epithelial stem cells reside in specific niches that regulate their self-renewal and differentiation, and are responsible for the continuous regeneration of tissues such as hair, skin, and gut.
Alonso, Maria T +9 more
core +4 more sources
Frontiers in Physiology, 2017 We have recently developed a novel in vitro model using HAT-7 rat ameloblast cells to functionally study epithelial ion transport during amelogenesis. Our present aims were to identify key transporters of bicarbonate in HAT-7 cells and also to examine ...
Róbert Rácz +9 more
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Deciphering the functions of Stromal Interaction Molecule-1 in amelogenesis using AmelX-iCre mice
Frontiers in Physiology, 2023 Introduction: The intracellular Ca2+ sensor stromal interaction molecule 1 (STIM1) is thought to play a critical role in enamel development, as its mutations cause Amelogenesis Imperfecta (AI).
Raed Said +10 more
doaj +1 more source
4-phenylbutyrate Mitigates Fluoride-Induced Cytotoxicity in ALC Cells
Frontiers in Physiology, 2017 Chronic fluoride over-exposure during pre-eruptive enamel development can cause dental fluorosis. Severe dental fluorosis is characterized by porous, soft enamel that is vulnerable to erosion and decay.
Maiko Suzuki +3 more
doaj +1 more source
The effect of inhibiting p38 MAPK on the expression of genes related to enamel development in mice
口腔疾病防治, 2021 Objective To study the effect of p38 mitogen activated protein kinase (p38 MAPK) on the expression of genes related to enamel development in the enamel epithelium and to provide a basis for the study of the molecular mechanism of enamel development ...
LUO Xiaona +4 more
doaj +1 more source
A secretory kinase complex regulates extracellular protein phosphorylation. [PDF]
, 2015 Although numerous extracellular phosphoproteins have been identified, the protein kinases within the secretory pathway have only recently been discovered, and their regulation is virtually unexplored.
Cui, Jixin +5 more
core +2 more sources
Intravesicular Phosphatase PHOSPHO1 Function in Enamel Mineralization and Prism Formation
Frontiers in Physiology, 2017 The transport of mineral ions from the enamel organ-associated blood vessels to the developing enamel crystals involves complex cargo packaging and carriage mechanisms across several cell layers, including the ameloblast layer and the stratum intermedium.
Mirali Pandya +7 more
doaj +1 more source
Calcium Sets the Clock in Ameloblasts
Frontiers in Physiology, 2020 BackgroundStromal interaction molecule 1 (STIM1) is one of the main components of the store operated Ca2+ entry (SOCE) signaling pathway. Individuals with mutated STIM1 present severely hypomineralized enamel characterized as amelogenesis imperfecta (AI)
Raed Said +5 more
doaj +1 more source
Energy metabolic shift contributes to the phenotype modulation of maturation stage ameloblasts
Frontiers in Physiology, 2022 Maturation stage ameloblasts (M-ABs) are responsible for terminal enamel mineralization in teeth and undergo characteristic cyclic changes in both morphology and function between ruffle-ended ameloblasts (RA) and smooth-ended ameloblasts (SA).
Haruno Arai +11 more
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