Results 301 to 310 of about 460,138 (357)

Crystal engineering of pharmaceutical co-crystals from polymorphic active pharmaceutical ingredients [PDF]

, 2009
Braga, Dario
core  

PSMD14 Stabilizes SLC7A11 to Ameliorate Glucocorticoid‐Induced Osteoporosis by Suppressing Osteocyte Ferroptosis

Advanced Science, EarlyView.
Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi, Qian Tang, Sunren Sheng, Hongyi Jiang, Chen Jin, Chencheng Zhou, Chenglong Xie, Lin Zheng, Di Zhang, Hui Xu, Cong Xu, Haiwei Ma, Guangheng Xiang, Wenfei Ni, Xiaoyun Pan, Lei Yang, Huazi Xu, Yu Qian, Aimin Wu, Xiangyang Wang, Gang Zheng   +20 more
wiley   +1 more source

Self‐Adaptive Reflectance Film for Passive Temperature Regulation in Diverse Environments

Advanced Science, EarlyView.
The rising demand for space cooling calls for innovative passive thermal systems. Traditional radiative cooling materials lack efficiency and alignment with cooling needs, limiting their energy‐saving. A smart film (PFSF) that integrates radiative cooling, reflectance tuning, and phase transition, offering adaptable temperature control across climates ...
Shuo Yang, Sizhe Tang, Yufeng Cai, Zhiming Ye, Xiangbin Zou, Xueyu Yuan, Yujie Song, Bing Li, Dongyan Tang, Ming Liu   +9 more
wiley   +1 more source

Characterization of Acid-Soluble Collagen From By-Product Bones of European Sea Bass (<i>Dicentrarchus labrax</i>) and Common Carp (<i>Cyprinus carpio</i>). [PDF]

Food Sci Nutr
Dikel Ç, Yanar Y.
europepmc   +1 more source

Noninvasive Assessment of β‐Secretase Activity Through Click Chemistry‐Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer's Disease

Advanced Science, EarlyView.
This study presents the NEV β‐secretase activity assay, a groundbreaking method for noninvasive evaluation of β‐secretase activity in Alzheimer's disease (AD) patients, enabling the generation of individualized β‐secretase activity profiles.
Hyoyong Kim, Junseok Lee, Audrey Qian, You‐Ren Ji, Ryan Zhang, Qixin Hu, Christopher Kazu Williams, Han‐Yu Chuang, Matthew D. Smalley, Yaya Xu, Liang Gao, Mary C. Mayo, Ting Zhang, Edwin M. Posadas, Zaldy S. Tan, Harry V. Vinters, Keith Vossel, Shino Magaki, Yazhen Zhu, Hsian‐Rong Tseng   +19 more
wiley   +1 more source

Synthesis and Conformational Analysis of <i>N</i>-Azulenyl-<i>N</i>-methyl Amides: Influence of Coplanarity on Amide Conformational Preference. [PDF]

ACS Omega
Ito A, Tsuchida A, Arakawa M, Yunoki M, Tomita M, Ishii A, Yamasaki R, Okamoto I.   +7 more
europepmc   +1 more source

Apoptotic Bodies Restore NAD and Mitochondrial Homeostasis in Fibroblasts

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived apoptotic bodies (MSC‐ABs) target keloid fibroblasts (KFs), restoring nicotinamide adenine dinucleotide (NAD) metabolism and mitochondrial function, suppressing collagen overproduction, and rebalancing tissue homeostasis, offering a novel therapy for keloid.
Shutong Qian, Siya Dai, Chunyi Guo, Wenjun Wang, Jiajia Pang, Yichen Shen, Mingyuan Xu, Jie Hu, Wenguo Cui, Xiaoming Sun, Jinghong Xu   +10 more
wiley   +1 more source

Advances in biosynthesis of chiral amide herbicides and the key enzymes: dimethenamid-P and S-metolachlor as case studies. [PDF]

Bioresour Bioprocess
Cheng F, Zhou YL, Yang DC, Zhao DY, Xue YP, Zheng YG.   +5 more
europepmc   +1 more source