Results 321 to 330 of about 291,669 (391)

Site-Selective Defluorinative sp3 C-H Alkylation of Secondary Amides.

Journal of the American Chemical Society, 2021
A site-selective defluorinative sp3 C-H alkylation of secondary amides that rapidly and reliably incorporates gem-difluoroalkene motifs into previously unfunctionalized sp3 sites is disclosed.
Wen‐Jun Yue, Craig S. Day, R. Martín
semanticscholar   +1 more source

Amide–Amide Hydrogen Bonding. Semirubin Amides

Monatshefte für Chemie - Chemical Monthly, 2006
Semirubins are analogs for one-half of the bilirubin structure and capable of intramolecular hydrogen bonding. Semirubin amides of ammonia and primary amines are also capable of intramolecular hydrogen bonding. From a combination of spectroscopic methods (1H NMR, NOE, and VPO), the primary amide is found to engage very effectively in intramolecular ...
Nicholas T. Salzameda, David A. Lightner
openaire   +2 more sources

Well-Defined Palladium(II)-NHC Precatalysts for Cross-Coupling Reactions of Amides and Esters by Selective N-C/O-C Cleavage.

Accounts of Chemical Research, 2018
Transition-metal-catalyzed cross-coupling reactions represent a most powerful tool for the rapid construction of C-C and C-X bonds available to synthetic chemists.
Shicheng Shi, S. Nolan, M. Szostak
semanticscholar   +1 more source

Amides

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Patrick D. Bailey, Richard A. Price, Rachel Pettecrew, Timothy J. Mills   +3 more
openaire   +2 more sources

Flexible and Chemoselective Oxidation of Amides to α-Keto Amides and α-Hydroxy Amides [PDF]

Journal of the American Chemical Society, 2017
A suite of flexible and chemoselective methods for the transition-metal-free oxidation of amides to α-keto amides and α-hydroxy amides is presented. These highly valuable motifs are accessed in good to excellent yields and stereoselectivities with high functional group tolerance.
Aurélien de la Torre, Daniel Kaiser, Nuno Maulide   +2 more
openaire   +3 more sources

Highly Chemoselective, Transition-Metal-Free Transamidation of Unactivated Amides and Direct Amidation of Alkyl Esters by N-C/O-C Cleavage.

Journal of the American Chemical Society, 2019
The amide bond is one of the most fundamental functional groups in chemistry and biology, and plays a central role in numerous processes harnessed to streamline the synthesis of key pharmaceutical and industrial molecules.
Guangchen Li, Chong-Lei Ji, Xin Hong, M. Szostak   +3 more
semanticscholar   +1 more source

NiH-Catalyzed Remote Asymmetric Hydroalkylation of Alkenes with Racemic α-Bromo Amides.

Angewandte Chemie, 2019
Reported here is a terminal-selective, remote asymmetric hydroalkylation of olefins with racemic α-bromo amides. The reaction proceeds by NiH-catalyzed alkene isomerization and subsequent alkylation reaction, and can enantioconvergently introduce an ...
F. Zhou, Yao-Wei Zhang, Xianfeng Xu, Shaolin Zhu   +3 more
semanticscholar   +1 more source

Reliable Determination of Amidicity in Acyclic Amides and Lactams [PDF]

The Journal of Organic Chemistry, 2012
Two independent computational methods have been used for determination of amide resonance stabilization and amidicities relative to N,N-dimethylacetamide for a wide range of acyclic and cyclic amides. The first method utilizes carbonyl substitution nitrogen atom replacement (COSNAR).
Adam A. Rosser, Stephen A. Glover
openaire   +2 more sources

On the relative strengths of amide…amide and amide…water hydrogen bonds

Chemical Physics Letters, 1991
We have performed Hayes—Stone intermolecular perturbation theory (IMPT) calculations on amide…water and amide…amide complexes in order to estimate the change ΔW in intermolecular interaction energy associated with the hydrogen bond exchange process amide(NH)…water+water…(OC)amide⇔amide(NH)…(OC)amide+water…water.
Sarah L. Price, John B. O. Mitchell
openaire   +2 more sources