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Novel Inhibitors of Brain, Neuronal, and Basophilic Anandamide Amidohydrolase
Biochemical and Biophysical Research Communications, 1997Mammalian brain as well as mouse neuroblastoma (N18TG2) and rat basophilic leukaemia (RBL) cells were previously shown to contain "anandamide amidohydrolase', a membrane-bound enzyme sensitive to serine and cysteine protease inhibitors and catalyzing the hydrolysis of the endogenous cannabimimetic metabolite, anandamide (arachidonoyl-ethanolamide ...
De Petrocellis L +7 more
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Inhibition of Serine Amidohydrolases by Complexes of Vanadate with Hydroxamic Acids
Biochemical and Biophysical Research Communications, 2000Serine beta-lactamases are inhibited by phosphonate monoester monoanions. These compounds phosphonylate the active site serine hydroxyl group to form inert, covalent complexes. Since spontaneous hydrolysis of these phosphonates is generally quite slow, the beta-lactamase active site must have considerable affinity for the (presumably) pentacoordinated ...
J H, Bell, K, Curley, R F, Pratt
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Anandamide Amidohydrolase from Porcine Brain
1997Ethanolamide of arachidonic acid was isolated from porcine brain as an endogenous ligand for cannabinoid receptors, and referred to as anandamide.1 In consideration of various biological activities of anandamide,2 it is very important to elucidate how the production and degradation of this new compound are regulated by enzymes within the cells.
Natsuo Ueda +3 more
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Arylamidase and amidohydrolases in soils as affected by liming and tillage systems
Soil and Tillage Research, 2004M A Tabatabai
exaly
Protonic reorganization and substrate structure in catalysis by amidohydrolases
Journal of the American Chemical Society, 1980Daniel M Quinn, Richard L Schowen
exaly