Results 91 to 100 of about 31,652 (216)
Multiphysics‐Driven Assembly of Biomimetic Vesicles
Advanced Materials, Volume 38, Issue 13, 3 March 2026.Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko +16 more
wiley +1 more source
Electrophysiology of Sodium Receptors in Taste Cells [PDF]
, 2016 Sodium intake is important to maintain proper osmolarity and volume of extracellular fluid in vertebrates. The ability to find sources of sodium ions for managing electrolyte homeostasis relies on the activity of the taste system to sense salt.
Bigiani, Albertino
core +1 more source
Advanced Science, Volume 13, Issue 17, 23 March 2026.A programmable nanoreactor was engineered for precise cGAS‐STING pathway activation in cancer immunotherapy. This strategy bridges targeted tumor DNA damage with DC immunomodulation, providing a translatable platform to unlock innate and adaptive antitumor immunity.
Shuang Liang +14 more
wiley +1 more source
Data in Brief, 2016 Positive DC (direct current) potentials were measured in the extracellular space in the retinal neuroepithelium of chick embryos. The positive DC potential was suppressed by amiloride, a blocker for epithelial Na+ channels (ENaC).
Masayuki Yamashita
doaj +1 more source
The effect of cyclophosphamide on salt taste in mice [PDF]
, 2016 Chemotherapy is a common cancer treatment, yet it has many severe side effects including altered taste. Patients report that salt taste is most affected by chemotherapy. The salt taste transduction system has yet to be fully elucidated.
Gomella, Michael
core +1 more source
Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation [PDF]
, 2014 Restoration of BECN1/Beclin 1-dependent autophagy and depletion of SQSTM1/p62 by genetic manipulation or autophagy-stimulatory proteostasis regulators, such as cystamine, have positive effects on mouse models of human cystic fibrosis (CF). These measures
Amin R +39 more
core +4 more sources
Contribution of the sympathetic nervous system to the pathogenesis of salt-sensitive hypertension [PDF]
, 2016 Dysregulation of the sodium-chloride cotransporter (NCC) is believed to significantly impact blood pressure. Recent studies have implicated overactivity of the sympathetic nervous system as a mechanism driving renal NCC dysregulation to evoke the ...
Pazzol, Michael Lee
core +1 more source
Exploring the cellular accumulation of metal complexes [PDF]
, 2010 Transition metal complexes offer great potential as diagnostic and therapeutic agents, and a growing number of biological applications have been explored. To be effective, these complexes must reach their intended target inside the cell.
Barton, Jacqueline K. +2 more
core +1 more source
Clinical Case Reports, Volume 14, Issue 3, March 2026.ABSTRACT Hypertension is common in autosomal‐dominant polycystic kidney disease (ADPKD) but may occasionally reflect a secondary etiology. We report a 71‐year‐old man with ADPKD and end‐stage renal disease who developed persistent, refractory hypertension following renal transplantation despite multidrug therapy and bilateral native nephrectomy ...
Matthew Wainstein +7 more
wiley +1 more source
Physiological levels of lipoxin A4 inhibit ENaC and restore airway surface liquid height in cystic fibrosis bronchial epithelium. [PDF]
, 2014 In cystic fibrosis (CF), the airway surface liquid (ASL) is depleted. We previously demonstrated that lipoxin A4 (LXA4) can modulate ASL height (ASLh) through actions on Cl(-) transport.
Al-Alawi, Mazen +8 more
core +5 more sources