Results 51 to 60 of about 16,803 (187)
Small, EarlyView.Cationic lipopeptides self‐assemble into stable, cell‐like vesicles that merge peptide programmability with lipid self‐organization. These biocompatible compartments efficiently sequester and deliver nucleic acids, enabling high transfection efficiency with low‐toxicity in both HEK293T cells and mesenchymal stem cells (MSCs).
Federica A. Souto‐Trinei +4 more
wiley +1 more source
The Role of Epithelial Sodium Channel ENaC and the Apical Cl-/HCO3- Exchanger Pendrin in Compensatory Salt Reabsorption in the Setting of Na-Cl Cotransporter (NCC) Inactivation. [PDF]
PLoS ONE, 2016 The absence of NCC does not cause significant salt wasting in NCC deficient mice under basal conditions. We hypothesized that ENaC and pendrin play important roles in compensatory salt absorption in the setting of NCC inactivation, and their inhibition ...
Mina Patel-Chamberlin +5 more
doaj +1 more source
Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges
The Chemical Record, EarlyView.Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen +3 more
wiley +1 more source
Development of New Thin-Film Micro-sensor for Potentiometric Determination of Amiloride
International Journal of Electrochemical Science, 2014 A new simple, selective, rapid and precise thin-film organic membrane based micro-sensor was developed for potentiometric determination of amiloride drug.
Hassan A. Arida +2 more
doaj +1 more source
Immunology &Cell Biology, EarlyView.VitBAg antigen presentation is promoted through a cytosolic pathway that reaches ligand‐receptive MR1 to present to MAIT cells, like the riboflavin transport pathway. Riboflavin solute carrier transporters can promote this MR1 presentation, but they are not essential for this role, suggesting redundant pathways to uptake VitBAg.
Sebastian Cruz‐Gomez +10 more
wiley +1 more source
Amiloride is neuroprotective in an MPTP model of Parkinson's disease
Neurobiology of Disease, 2008 The diuretic amiloride has recently proven neuroprotective in models of cerebral ischemia, a property attributable to the drug's inhibition of central acid-sensing ion channels (ASICs).
Robert L. Arias +13 more
doaj +1 more source
Lifestyle Medicine, Volume 7, Issue 3, July 2026.ABSTRACT Introduction Hypertension and Type 2 diabetes are major contributors to the growing burden of non‐communicable diseases in rural Zambia. Lifestyle interventions are central to prevention and management, yet implementation remains limited in resource‐constrained settings.
Keith Birrell +2 more
wiley +1 more source
The Saudi Journal of Gastroenterology, 2015 Background/Aim: Aerobic metabolism is necessary for ion transport in many transporting epithelia, including the human colonic epithelium. We assessed the effects of the epithelial sodium channel blocker, amiloride, on oxygen consumption and short-circuit
Graciela E Carra +3 more
doaj +1 more source
Diamine oxidase is the amiloride-binding protein and is inhibited by amiloride analogues
Journal of Biological Chemistry, 1994 Diamine oxidase (histaminase), an enzyme that oxidatively deaminates putrescine and histamine, was purified from human placenta and from pig kidney. Both NH2-terminal sequences are highly homologous to the human kidney amiloride-binding protein, previously thought to be a component of the amiloride-sensitive Na+ channel.
W F, Novotny +4 more
openaire +2 more sources