Results 81 to 90 of about 31,652 (216)
Acta Ophthalmologica, EarlyView.Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen +3 more
wiley +1 more source
The Saudi Journal of Gastroenterology, 2015 Background/Aim: Aerobic metabolism is necessary for ion transport in many transporting epithelia, including the human colonic epithelium. We assessed the effects of the epithelial sodium channel blocker, amiloride, on oxygen consumption and short-circuit
Graciela E Carra +3 more
doaj +1 more source
SPX-101 is stable in and retains function after exposure to cystic fibrosis sputum [PDF]
, 2019 Background: In healthy lungs, epithelial sodium channel (ENaC) is regulated by short, palate, lung, and nasal clone 1 (SPLUNC1). In cystic fibrosis (CF), ENaC is hyperactivated in part due to a loss of SPLUNC1 function.
Scott, David W. +3 more
core +1 more source
Journal of Fish Biology, EarlyView.Abstract The branchial epithelium of Potamotrygon—a member of the only strictly freshwater elasmobranch family Potamotrygonidae—was observed via immunohistochemistry, and two distinct forms of ionocytes were identified. The acid (A‐type) and base (B‐type) secreting cells with respective basolateral–apical localizations of Na+/K+‐ATPase–Na+/H+ exchanger
M. W. Rossi +3 more
wiley +1 more source
A minireview on NHE1 inhibitors. A rediscovered hope in oncohematology
Biomedical Papers, 2015 Background: Na+/H+ exchanger-1 (NHE-1) is involved in pH regulation and is up-regulated in different malignancies. Activation of NHE-1 is one way for allowing cells to avoid intracellular acidification and protect them against apoptosis.
Romeo Gabriel Mihaila
doaj +1 more source
Cell volume regulation by Amphiuma red blood cells. The role of Ca+2 as a modulator of alkali metal/H+ exchange. [PDF]
, 1983 In response to osmotic perturbation, the Amphiuma red blood cell regulates volume back to "normal" levels. After osmotic swelling, the cells lose K, Cl, and osmotically obliged H2O (regulatory volume decrease [RVD] ). After osmotic shrinkage, cell volume
Cala, PM
core
The Journal of Physiology, EarlyView.Abstract figure legend 6‐Methylsulfinylhexyl isothiocyanate (6‐MSITC, hexaraphane), a wasabi sulfinyl compound, activates intracellular carbonic anhydrase (CA)‐mediated sequential HCO3−, Na+, H+ and Ca2+ transport through an activation axis involving HCO3−‐transporting solute carrier family 4 (SLC4As), the Na+–H+ exchanger (NHE), the Na+–Ca2+ exchanger
Yoshiaki Furusawa +9 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi +6 more
wiley +1 more source
Mechanosensor Channels in Mammalian Somatosensory Neurons
Sensors, 2007 Mechanoreceptive sensory neurons innervating the skin, skeletal muscles andviscera signal both innocuous and noxious information necessary for proprioception, touchand pain.
Patrick Delmas +8 more
doaj +1 more source
Acid-sensing ion channel 3 decreases phosphorylation of extracellular signal-regulated kinases and induces synoviocyte cell death by increasing intracellular calcium. [PDF]
, 2014 IntroductionAcid-sensing ion channel 3 (ASIC3) is expressed in synoviocytes, activated by decreases in pH, and reduces inflammation in animal models of inflammatory arthritis.
Boyle, David L +6 more
core +2 more sources