Results 191 to 200 of about 68,101 (292)

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu   +9 more
wiley   +1 more source

Identification and Evaluation of Olive Phenolics in the Context of Amine Oxidase Enzyme Inhibition and Depression: In Silico Modelling and In Vitro Validation. [PDF]

open access: yesMolecules
Karagiannis TC   +13 more
europepmc   +1 more source

Effect of Cell Disruption and Protein Extraction on the Structural and Technological Properties of Tetradesmus obliquus Protein‐Rich Extracts

open access: yesSustainable Food Proteins, Volume 4, Issue 2, June 2026.
Despite its considerable potential as a functional food ingredient, T. obliquus faces a major limitation in protein recovery due to the rigidity of its cell wall. In the microalgae industry, protein extraction typically involves two main steps: cell disruption and protein extraction.
César Augusto Sodré da Silva   +6 more
wiley   +1 more source

Understanding the riddle of amine oxidase flavoenzyme reactivity on the stereoisomers of N-methyl-dopa and N-methyl-tyrosine. [PDF]

open access: yesJ Mol Recognit
Gracia Carmona O   +7 more
europepmc   +1 more source

AMINE OXIDASES

open access: yesJournal of Biological Chemistry, 1957
James R. Fouts   +3 more
openaire   +1 more source

Allele‐informed QTL‐seq identifies Hd18 as a minor modifier of heading date in elite rice cultivars

open access: yesThe Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Fine‐tuning heading date is critical for optimizing yield, grain quality, and local adaptation in rice (Oryza sativa L.). QTL‐seq (where QTL is quantitative trait locus), which integrates bulked segregant analysis with whole‐genome resequencing, provides a rapid and cost‐effective approach for identifying QTLs underlying complex traits ...
Hayeong Lee   +5 more
wiley   +1 more source

Identification of 2‐Substituted‐3‐Hydroxy‐2,3‐Dihydroquinazolin‐4(1H) Ones as Cell‐Active Inhibitors of KDM4A Lysine Demethylase

open access: yesChemMedChem, Volume 21, Issue 10, 27 May 2026.
A novel 3‐hydroxy‐2,3‐dihydroquinazolinone scaffold is identified as a cell‐active KDM4A inhibitor through an orthogonal screening cascade minimizing assay interference. Integrated biochemical, biophysical, and proteomic validation reveals compound 6i as a bona fide binder that increases H3K9 methylation in cells, highlighting both a promising ...
Alessandra Feoli   +13 more
wiley   +1 more source

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