STUDIES ON AMINE OXIDASE I. REDUCTION OF CYTOCHROME C BY HISTAMINE AND OTHER PHARMACOLOGICAL AMINES
Akira Hoshika
openalex +1 more source
Investigating operational stability and causes of cofactor release in fold type I amine transaminase
Abstract Amine transaminases (ATAs) are pyridoxal phosphate (PLP) dependent biocatalysts frequently employed in chiral amine synthesis. Yields of ATA‐catalyzed reactions often suffer from low enzyme operational stability due to weak interactions between the ATA and the aminated cofactor pyridoxamine phosphate (PMP), which can leak from the active site ...
Xuebin Feng +2 more
wiley +1 more source
An enantioconvergent approach for the kinetic resolution of S(VI) stereocenters that leverages the electrophilic reactivity of the chiral sulfur atom is described. The catalytic process provides access to sulfonimidoyl chlorides and sulfonimidates, which are among the least studied S(VI) functionalities.
Arko Das +10 more
wiley +2 more sources
Amine Oxidase, Copper Containing 3 (Aoc3) Knockout Mice Are More Prone to DSS-induced Colitis and Colonic Tumorigenesis. [PDF]
Özcan Ö, Akyol Ö, Akyol A.
europepmc +1 more source
Molecular mechanism of a large conformational change of the quinone cofactor in the semiquinone intermediate of bacterial copper amine oxidase. [PDF]
Shoji M +6 more
europepmc +1 more source
ECUT (Energy Conversion and Utilization Technologies) program: Biocatalysis Project [PDF]
Fiscal year 1987 research activities and accomplishments for the Biocatalysis Project of the U.S. Department of Energy, Energy Conversion and Utilization Technologies (ECUT) Division are presented.
core +1 more source
Replacement of Tyrosines by Unnatural Amino Acid Aminophenylalanine Leads to Metal-Mediated Aniline Free Radical Formation in a Copper Amine Oxidase. [PDF]
Koehn EM +4 more
europepmc +1 more source
Mechanisms of spermine toxicity in baby-hamster kidney (BHK) cells. The role of amine oxidases and oxidative stress [PDF]
Val Brunton, Mark Grant, Heather Wallace
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Alcohol dehydrogenases (ADHs) are best known for reducing ketones to chiral alcohols, but their oxidative potential is rarely exploited. Here, we show that selected ADHs catalyze newly discovered promiscuous transformations: the oxidative coupling of primary alcohols with amines or thiols, enabling the direct and efficient synthesis of a broad range of
Matteo Damian +4 more
wiley +2 more sources
[Functional study of amine oxidase copper-containing 1 (AOC1) in lipid metabolism]. [PDF]
Xiang S, Liu S, Li K, Zhao T, Wang X.
europepmc +1 more source

