Results 41 to 50 of about 71,396 (331)

Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity [PDF]

open access: yes, 2019
A series of benzo[b]thiophen-3-ols were synthesised and investigated as potential human monoamine oxidase (hMAO) inhibitors in vitro as well as ex vivo in rat cortex synaptosomes by means of evaluation of 3,4-dihydroxyphenylacetic acid/dopamine (DOPAC/DA)
Alcaro, Stefano   +13 more
core   +1 more source

Bioconversion of Airborne Methylamine by Immobilized Recombinant Amine Oxidase from the Thermotolerant Yeast Hansenula polymorpha

open access: yesThe Scientific World Journal, 2014
Aliphatic amines, including methylamine, are air-pollutants, due to their intensive use in industry and the natural degradation of proteins, amino acids, and other nitrogen-containing compounds in biological samples.
Sasi Sigawi   +5 more
doaj   +1 more source

Microarray studies on the effect of silencing tynA in Escherichia coli K-12

open access: yesGenomics Data, 2016
To study the biological role of the tynA gene product of Escherichia coli, a primary amine oxidase (ECAO, E.C. 1.4.3.21), the tynA gene was genetically silenced by conjugation with a kanamycin resistance cassette.
Heli Elovaara
doaj   +1 more source

Histamine intolerance caused by Diamine Oxidase (DAO) deficiency – case report

open access: yesJournal of Pre-Clinical and Clinical Research, 2022
Histamine is a biogenic amine, which occurs naturally in the human body. Histamine can be metabolised with Diamine Oxidase (DAO) Enzyme. It is estimated that in 1% of people, as a result of an imbalance between the supply and degradation of histamine, a ...
Aleksandra Iwona Zimna   +5 more
doaj   +1 more source

Pharmacology and clinical drug candidates in redox medicine [PDF]

open access: yes, 2015
SIGNIFICANCE Oxidative stress is suggested to be a disease mechanism common to a wide range of disorders affecting human health. However, so far, the pharmacotherapeutic exploitation of this, for example, based on chemical scavenging of pro-oxidant ...
Casas, Ana I   +11 more
core   +3 more sources

Serum level of semicarbazide-sensitive amine oxidase in children with ADHD

open access: yesBehavioral and Brain Functions, 2006
Background The objective of this study was to analyze the extracellularly acting semicarbazide-sensitive amine oxidase (SSAO) serum levels in children with ADHD for the first time. SSAO is known to show deviations from normal in various somatic disorders
Bleich Stefan   +5 more
doaj   +1 more source

Plant Polyamines

open access: yesPlants, 2020
Polyamines are small organic compounds found in all living organisms. According to the high degree of positive charge at physiological pH, they interact with negatively charged macromolecules, such as DNA, RNA, and proteins, and modulate their activities.
Taku Takahashi
doaj   +1 more source

A uracil nitroso amine based colorimetric sensor for the detection of Cu²⁺ ions from aqueous environment and its practical applications [PDF]

open access: yes, 2015
A simple uracil nitroso amine based colorimetric chemosensor (UNA-1) has been synthesized and screened for its cation recognition ability. Sensor UNA-1 exhibited a high sensitivity and selectivity towards Cu²⁺ ions in aqueous medium in the presence of a ...
Chen, Lingxin   +10 more
core   +2 more sources

The role of “semicarbazide-sensitive amine oxidase” in the arterial wall

open access: yesArtery Research, 2009
“Semicarbazide-sensitive amine oxidase” (SSAO) metabolizes primary amines into aldehydes, hydrogen peroxide and ammonia and is largely expressed in adipocytes, lymphatic endothelial cells and vascular smooth muscle cells (VSMCs). In vitro SSAO expression
N. Mercier
doaj   +1 more source

Inhibitor specificity of amine oxidase [PDF]

open access: yes, 1943
Although at the present time it appears clear that amine oxidase oxidation of adrenalin, or other o-diphenolic pressor amines such as were studied by Richter (6), does not play a significant physiological role, it is equally clear that the inactivation ...
Alles, Gordon A., Heegaard, Erik V.
core  

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