Results 51 to 60 of about 29,882 (228)
Advanced Science, EarlyView.Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong +9 more
wiley +1 more source
Advanced Science, EarlyView.Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong +13 more
wiley +1 more source
International Journal of Nanomedicine, 2012 Giulietta Sinigaglia1, Massimiliano Magro1, Giovanni Miotto1, Sara Cardillo1, Enzo Agostinelli2,3, Radek Zboril4, Eris Bidollari2,3, Fabio Vianello11Department of Biological Chemistry, University of Padua, Padua, Italy; 2Istituto Pasteur-Fondazione Cenci
Bidollari E +7 more
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Phenelzine: An old drug that may hold clues to the development of new neuroprotective agents
Psychiatry and Clinical Psychopharmacology, 2021 The monoamine oxidase (MAO)-inhibiting antidepressant phenelzine (PLZ) is also used in the treatment of anxiety disorders such as panic disorder and social anxiety disorder and has been shown to have neuroprotective actions in an animal model of ...
Erin M. MacKenzie +5 more
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Studia Universitatis Babes-Bolyai Chemia, 2020 Grass pea amine oxidase (GPAO) and oat polyamine oxidase (OPAO) were immobilized along with horseradish peroxidase (HRP) and an Os-redox polymer (Os-RP) onto the surface of a graphite electrode by cross-linking with poly(ethylenglycol) diglycidyl ether.
Laura AQUILANTE +5 more
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Advanced Science, EarlyView.Synovial macrophages in osteoarthritis upregulate LSP1, which directly binds and inhibits SOD1, triggering a redox imbalance that activates both NOX and mitochondrial ROS pathways. This cascade drives the release of macrophage extracellular traps (METs), causing chondrocyte damage and disease progression.
Yankai Pan +9 more
wiley +1 more source
SUATU KAJIAN MOLEKULER KETERGANTUNGAN NIKOTIN
Jurnal Farmasi Sains dan Komunitas, 2016 : Nicotine, a simple chemical substance from tobacco, stimulates addiction by neuroadaptation inducing rewards system in human brain. Molecular mechanism of nicotine addiction in rewards system are mediated by nicotinic acetylcholine receptor (nAChR) and
Agustina Setiawati
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Amine Oxidases of Marine Phytoplankton [PDF]
Applied and Environmental Microbiology, 1991 Some phytoplankton utilized a novel mechanism for obtaining nitrogen from primary amines. They oxidized the primary amines to produce extracellular hydrogen peroxide and aldehydes and used the third reaction product, ammonium, as a nitrogen source. The specificity, regulation, inhibition by bromoethylamine, and potential dependence on copper of this ...
B, Palenik, F M, Morel
openaire +2 more sources
Porphyrin‐Based Porous Materials for Antibacterial Applications
Advanced Science, EarlyView.Porphyrin‐based porous materials have excellent photophysical properties and tunable structures for high‐efficiency antibacterial therapy. This review comprehensively discusses the structural design strategies and synthetic pathways of the four main types of porphyrin‐based porous materials, summarizes their cross‐domain antimicrobial applications, and
Xiao‐Xue Liang +4 more
wiley +1 more source
مجلة بغداد للعلوم, 2019 Allopurinol derivative were prepared by reacting the (1-chloroacetyl)-2-Hydropyrazolo{3,4-d}pyrimidine-4-oneiwith 5- methoxy- 2-aminoibenzothiazoleiunder certain conditions to obtain new compound ( N- (2-aminoacetyl (5-methoxy) benzothiazole -2yl) (A4),
Khammas et al.
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