Results 91 to 100 of about 7,123 (216)

Microfabricated Neural Biosensors for Detection of Neurotransmitters, Biomarkers, and Small Molecules: Emerging Trends on Self‐Sustained Systems and Energy Harvesting

Advanced Sensor Research, Volume 5, Issue 1, January 2026.
This paper reviews the state of the art and recent developments in thin‐film biosensors for the detection of neurotransmitters, small molecules, and biomarkers within flexible, implantable bioelectronic systems. It covers the main sensing modalities, including electrochemical, plasmonic, acoustic, and magnetic, alongside their materials, transduction ...
Massimo Mariello
wiley   +1 more source

Metallothionein‐Inspired Asymmetric Heteroatom Doping of Single‐Atom Nanozymes for Multi‐Enzyme Biocatalysis

Advanced Science, Volume 13, Issue 5, 27 January 2026.
A metallothionein‐inspired heteroatom doping strategy is reported to construct asymmetric Fe single‐atom catalysts, which display markedly enhanced multi‐enzyme activities—including NADH oxidase‐, oxidase‐, peroxidase‐, and catalase‐like activities. This high multi‐enzyme efficiency arises from atomically dispersed Fe from biomineralization, the large ...
Kaijuan Chen, Qianfan Chen, Bernt Johannessen, Chun‐Ho Lin, Long Hu, Kang Liang, Jieying Liang   +6 more
wiley   +1 more source

Mechanistic Insights Into Copper Aggregates With Unsymmetrical Coordination Environments: From Biomimetic Copper–Oxygen Model Complexes to Copper–Alkynyl Clusters

Aggregate, Volume 7, Issue 1, January 2026.
Copper aggregates with unsymmetrical coordination environments play the pivotal role in many biological and organocatalytic transformations due to their differentiated redox properties and biological functions. The new concept for the “[Cu–O] + [Cu–alkynyl]” bi‐cluster aggregate is discussed in detail to clarify the distinctive structure–property ...
Siqi Zhang, Wen‐Shan Liu, Liang Zhao
wiley   +1 more source

Nanobiotechnology‐Based Approaches for Targeted Glioma Therapy

Advanced NanoBiomed Research, Volume 6, Issue 1, January 2026.
Nanoparticle systems cross the blood–brain barrier to deliver drugs precisely to glioma cells. Lipid, polymeric, and magnetic carriers enable controlled release, tumor targeting, and microenvironment modulation. These nanoplatforms enhance chemotherapy, radiotherapy, and immunotherapy, improving therapeutic efficacy while reducing systemic toxicity ...
Jinwei Li, Yibo He, Yang Zhang, Lining Arnold Ju, Yao Wang, Jianxuan Zhou, Yinying Chai, Xuhui Hui, ShiYuan Tong, Si Zhang, Yanli Tan, Yinyan Wang   +11 more
wiley   +1 more source

Development of New Benzo[b]Thiophene‐2‐Carboxamide Derivatives as Advanced Glycation End‐Products Receptor (RAGE) Antagonists

ChemMedChem, Volume 21, Issue 1, January 2026.
A streamlined Ullmann‐Goldberg strategy enabled the synthesis of benzo[b]thiophene‐2‐carboxamides, promising ligands of the pro‐inflammatory RAGE receptor involved in inflammaging and age‐related diseases. LC‐MS, NMR, X‐ray and DFT studies elucidated the copper‐catalyzed mechanism. The lead compound, 3t’, shows inhibitory activity on the sRAGE/AGE2‐BSA
Lisa Bonin, Matthieu Hedouin, Christophe Furman, Ophélie Not, Steve Lancel, Mona Bensalah, Gael Coadou, Eric Boulanger, Sergiu Shova, Hassan Oulyadi, Alina Ghinet   +10 more
wiley   +1 more source

Piperazine Derivatives: A Privileged Scaffold in Modern Synthesis and Medicinal Chemistry

ChemistryOpen, Volume 15, Issue 1, January 2026.
Piperazine‐based bioactive molecules represent a versatile class of compounds with broad therapeutic potential. Structural modification of the piperazine scaffold governs key structure–activity relationships, enabling antibacterial, antifungal, antitumor, neuroactive, and anti‐inflammatory activities.
Assel Ten, Raushan Koizhaiganova, Dilnaz Bissenbay, Bagila Tursynova, Zhanar Zhaxibayeva, Valentina Yu   +5 more
wiley   +1 more source

A C-terminal disulfide bond in the copper-containing amine oxidase from pea seedlings violates the twofold symmetry of the molecular dimer

, 2006
Anthony P. Duff, Eric M. Shepard, David B. Langley, David M. Dooley, Hans C. Freeman, J.M. Guss   +5 more
openalex   +1 more source

Copper-containing amine oxidases contribute to terminal polyamine oxidation in peroxisomes and apoplast of Arabidopsis thaliana [PDF]

, 2013
Joan Planas-Portell, Marta Gallart, Antonio F. Tiburcio, Teresa Altabella   +3 more
openalex   +1 more source

Functionalizing Nucleic Acids: Synthesis and Purification Strategies for Bioconjugates as Biomaterials

Small, Volume 22, Issue 5, 22 January 2026.
Nucleic acid‐ligand conjugates combine the distinct properties of macromolecular ligands with the versatility of DNA/RNA nanotechnology. In biomaterial and nanomedicine applications, highly purified products are paramount, requiring reliable synthesis and purification methods.
Nico Alleva, Jian Zhang, David Y. W. Ng, Tanja Weil, Torsten John   +4 more
wiley   +1 more source

Emerging Biomedical Engineering Therapies for Infected Diabetic Foot Ulcers: Toward Antibacterial Functionalization and Pathology‐Responsive Regulation

Small Science, Volume 6, Issue 1, January 2026.
Infected diabetic foot ulcer endangers patients with high amputation, disability, mortality risks, and heavy medical burdens. This review analyzes its pathogenic factors, the limitations of current treatments, the breakthroughs of responsive antimicrobial biomaterials, and the challenge of multifunctional biomaterial innovations for further developing ...
Yaqi Yao, Mengyi Huang, Yuetong Li, Yiqi Lin, Junjie Dong, Jianhang Du, Aixia Zhai, Changlong Bi, Luoyuan Li   +8 more
wiley   +1 more source