Results 131 to 140 of about 3,407,324 (358)

Natural variation in the OsbZIP18 promoter contributes to branched‐chain amino acid levels in rice [PDF]

, 2020
Yangyang Sun, Yuheng Shi, Guige Liu, Fang Yao, Yuanyuan Zhang, Chenkun Yang, Hao Guo, Xianqing Liu, Cheng Jin, Jie Luo   +9 more
openalex   +1 more source

Amino Acids and Hemodialysis [PDF]

The International Journal of Artificial Organs, 1981
Tepper, T, van der Hem, GK
openaire   +3 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Rate constants measured for hydrated electron reactions with peptides and proteins [PDF]

, 1968
Effects of ionizing radiation on the amino acids of proteins and the reactivity of the protonated amino group depends upon the pK subscript a of the group.
Braams, R.
core   +1 more source

Symmetry Scheme for Amino Acid Codons

, 2003
Group theoretical concepts are invoked in a specific model to explain how only twenty amino acids occur in nature out of a possible sixty four. The methods we use enable us to justify the occurrence of the recently discovered twenty first amino acid ...
F. Zinoni, G. E. Garcia, I. Chambers, J. Balakrishnan, J. E. M. Hornos, J. E. M. Hornos, J. E. M. Hornos, J. F. Atkins, J. L. Cornette, M. Forger, M. J. Berry, R. Slansky   +11 more
core   +1 more source

Amino acid sensing in cancer

Pharmacological Research
Tumour progression is accompanied by metabolic reprogramming, enabling adaptation to the nutrient-deprived microenvironment. Amino acids, as key metabolic substrates, play a central role in metabolic reprogramming.
Zihao Lin, Lihong He, Jiawei Wang, Hanjia Zhang, Shicheng Yao, Jingpeng Guo, Xiaozhen Zhang, Tingbo Liang, Xueli Bai   +8 more
doaj   +1 more source

Effects of glutamate and aspartate on growth performance, serum amino acids, and amino acid transporters in piglets

Food and Agricultural Immunology, 2018
This study mainly investigated the effects of different dietary levels of glutamate (Glu) and aspartate (Asp) on growth performance, blood amino acids, and amino acid transporters in piglets.
Yuying Li, Hui Han, Jie Yin, Jie Zheng, Xiaotong Zhu, Tiejun Li, Yulong Yin   +6 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Preparation of Translationally Competent tRNA by Direct Chemical Acylation [PDF]

, 2010
Nonsense codon suppression for unnatural amino acid incorporation requires the preparation of a suppressor aminoacyl-tRNA. Chemical acylation strategies are general but inefficient and arduous. A recent report (J. Am. Chem. Soc.
Dougherty, Dennis A., Duffy, Noah H.
core   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source