Results 161 to 170 of about 7,026,669 (342)

THE REACTIONS OF AMINO AND IMINO ACIDS WITH FORMALDEHYDE

, 1937
Milton Levy, David E. Silberman
openalex   +1 more source

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

FEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi, Saki Sugihara, Yohei Ishibashi, Kono Yushi, Hazuki Yamauchi, Motohiro Tani   +5 more
wiley   +1 more source

Mammalian Tolerance to Amino Acid Heterochirality. [PDF]

Chembiochem
Taniguchi S, Adachi K, Tran X, Suzuki M, Sasabe J.   +4 more
europepmc   +1 more source

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra, Sara Bernal, David Almenta, Josefina Pérez‐Blanco, Valle Camacho, Isabel Sala, Mª Belén Sánchez‐Saudinós, Jesús García Castro, Judit Selma‐González, Miguel Ángel Santos‐Santos, Álvaro Carbayo, Janina Turon‐Sans, Ricard Rojas‐Garcia, Daniel Alcolea, Juan Fortea, Alberto Lleó, Oriol Dols‐Icardo, Ignacio Illán‐Gala   +17 more
wiley   +1 more source

Branched-chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control

Nature Metabolism, 2019
Samantha M. Solon-Biet, V. Cogger, T. Pulpitel, Devin Wahl, Ximonie Clark, Elena E Bagley, Gabrielle C Gregoriou, A. Senior, Qiao-Ping Wang, A. Brandon, Ruth Perks, J. O’Sullivan, Y. Koay, K. Bell‐Anderson, M. Kebede, B. Yau, Clare Atkinson, G. Svineng, Tim Dodgson, J. A. Wali, M. Piper, Paula Juricic, L. Partridge, A. Rose, D. Raubenheimer, G. Cooney, D. L. Le Couteur, S. Simpson   +27 more
semanticscholar   +1 more source

Targeting amino acid in tumor therapy. [PDF]

Front Oncol
Ge M, Xu Y, Cui L, Huang E, Liu Z, Yin K.   +5 more
europepmc   +1 more source

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes

Science, 2017
Monther Abu-Remaileh, Gregory A. Wyant, Choah Kim, N. N. Laqtom, M. Abbasi, Sze Ham Chan, Elizaveta Freinkman, D. Sabatini   +7 more
semanticscholar   +1 more source

A Novel C19orf47‐AKT2 Chimeric RNA Generated by Cis‐Splicing of Adjacent Genes Is Associated With Glioblastoma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Malignant gliomas pose significant therapeutic challenges. This study aimed to identify and characterize a novel chimeric RNA in glioma and assess its clinical and functional significance for precision treatment. Methods The C19orf47‐AKT2 chimeric RNAs were identified through RNA sequencing and validated by polymerase chain reaction.
Zihan Wang, Bowen Ni, Kezhi Wu, Qi Zhang, Jinglin Guo, Runwei Yang, Ziyu Wang, Guozhong Yi, Guanglong Huang, Minyi He, Yimin Xu, Yawei Liu   +11 more
wiley   +1 more source

Amino-acid content of raw and heat-sterilized cow's milk [PDF]

, 1959
Sheila Payne-Botha, E. J. Bigwood
openalex   +1 more source