Results 21 to 30 of about 1,964,821 (266)
Research progress on branched-chain amino acid aminotransferases
Frontiers in Genetics, 2023 Branched-chain amino acid aminotransferases, widely present in natural organisms, catalyze bidirectional amino transfer between branched-chain amino acids and branched-chain α-ketoacids in cells.
Can Chen +3 more
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Physiology of the Amino Acids [PDF]
Science, 1942 We have followed the amino acids from their entrance into the alimentary tract in the form of food proteins through the successive steps of digestion, absorption into the blood stream and passage from the blood stream into the tissues, where they are concentrated by some unknown mechanism to many times their concentration in the blood plasma.
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AnimalsTwo 35-day trials were conducted to determine the arginine (Arg) requirement of broiler chickens and the Arg and energy-sparing effects of guanidinoacetic acid (GAA). In experiment 1, a low-Arg diet (basal diet) was supplemented with increasing levels (0.
Adriaan Verhelle, Behnam Saremi
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Amino Acid Metabolism in Lupus
Frontiers in Immunology, 2021 T cell metabolism is central to cell proliferation, survival, differentiation, and aberrations have been linked to the pathophysiology of systemic autoimmune diseases.
Michihito Kono +2 more
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Amino Acids, Amino Acid Derivatives and Peptides as Antioxidants
, 2022 [Excerpt] The biological concept of antioxidant refers to any compound that is able to delay or 5 prevent the oxidation of easily oxidizable substrates, such as DNA, proteins and 6 lipids. Antioxidants reduce oxidative stress and mutations in DNA as well as other 7 parameters associated with cell damage.
Monteiro, Luís S. +1 more
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Research Progress of Amino Acid Metabolism PET Imaging in Tumor
Journal of Isotopes, 2015 Amino acid metabolism PET imaging plays a very important role in metabolism molecular imaging. Amino acid PET tracers include ［1-11C］amino acid, labeling α-C amino acid, labeling side-chain amino acid, and N-substituted labeling amino acid.
NIE Da-hong, TANG Gang-hua2
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
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Role of amino acid transporters in amino acid sensing [PDF]
The American Journal of Clinical Nutrition, 2014 Amino acid (AA) transporters may act as sensors, as well as carriers, of tissue nutrient supplies. This review considers recent advances in our understanding of the AA-sensing functions of AA transporters in both epithelial and nonepithelial cells.
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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