Results 41 to 50 of about 2,226,397 (316)

ProRepeat: an integrated repository for studying amino acid tandem repeats in proteins

, 2011
ProRepeat (http://prorepeat.bioinformatics.nl/) is an integrated curated repository and analysis platform for in-depth research on the biological characteristics of amino acid tandem repeats.
Harm Nijveen, Lin, K., Jack A. M. Leunissen, K. Lin, Audrey David, Luo, H., Ke Lin, A. David, David, A., H. Nijveen, H. Luo, Leunissen, J.A.M., Nijveen, H., Hong Luo, J. A. M. Leunissen   +14 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

AMINO ACID PROFIL OF EARTHWORM AND EARTHWORM M AL (Lumbricus rubellus )FOR ANIMAL F DSTUFF [PDF]

, 2009
Earthworm meal (Lumbricus rubellus has become one of natural material that could be used as feed additive.Powdering method of earthworm was done by using formic acid addition.The study was carried out (1)to evaluate the essential amino acid profile of ...
Sofyan, A, Damayanti, E, Julendra, H, Istiqomah, L   +3 more
core  

Amino acid transporter genes are essential for FLO11-dependent and FLO11-independent biofilm formation and invasive growth in saccharomyces cerevisiae

, 2012
Amino acids can induce yeast cell adhesion but how amino acids are sensed and signal the modulation of the FLO adhesion genes is not clear. We discovered that the budding yeast Saccharomyces cerevisiae CEN.PK evolved invasive growth ability under ...
Eckhard Boles, Sefa Alizadeh, Eckhard Boles (148580), Henrik Devitt Møller (148562), Møller, Henrik Devitt, Doreen Ochmann (148576), Møller, Henrik D., Gresham, David, Ochmann, Doreen, Doreen Ochmann, Torbensen, Rasmus, Birgitte Regenberg, Rasmus Torbensen, David Gresham (148568), Boles, Eckhard, Regenberg, Birgitte, Henrik Devitt Møller, Birgitte Regenberg (24433), Rasmus Torbensen (148554), Sefa Alizadeh (148573), Alizadeh, Sefa, David Gresham   +21 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Plasma amino acid profiles in pediatric obesity: potential biomarkers for the early assessment of metabolic risk

Frontiers in Pediatrics
IntroductionChildhood obesity is among the most serious and rapidly growing public health issues globally. Although body mass index (BMI) is commonly used to evaluate obesity, it does not always reflect early metabolic disturbances.
Ece Öge Enver, Aydın Duygu, Pınar Vatansever, Bilal Yılmaz, Yasemin Akın   +4 more
doaj   +1 more source

Analysis of Main Tea Characteristic Components and Volatile Components and Amino Acid Nutrition Evaluation of Insect Tea from Three Producing Areas in Guangxi

Shipin gongye ke-ji, 2022
The main tea characteristic components, volatile components and amino acid composition of insect tea from three main producing areas in Guangxi were analyzed in this paper, and the amino acid characteristics and nutritional value were evaluated by amino ...
Lixiang WEN, Dongyin YUAN, Shuqiong OU, Fen ZHANG, Jiaxian CHEN, Shouhui HUANG, Chunmei FENG, Jingru PENG   +7 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Effect of oxygen tension on the amino acid utilisation of human embryonic stem cells

, 2014
Background/aims: human embryonic stem cells (hESCs) are a potential source of cells for treatment of many degenerative diseases, but in culture have a propensity to spontaneously differentiate, possibly due to suboptimal conditions. Culture at low oxygen
Christensen, David R., David R. Christensen, Calder, Philip C., Houghton, Franchesca D., Philip C. Calder, Franchesca D. Houghton   +5 more
core   +1 more source

GSK3-mediated raptor phosphorylation supports amino acid-dependent Q2 mTORC1-directed signalling [PDF]

, 2015
The mammalian or mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) is a ubiquitously expressed multimeric protein kinase complex that integrates nutrient and growth factor signals for the co-ordinated regulation of cellular metabolism and cell ...
Stretton, Clare, Taylor, Peter M., Hundal, Harinder, Prescott, Alan; id_orcid, Hoffmann, Thorsten M., Ganley, Ian G.; id_orcid, Munson, Michael J.   +6 more
core   +1 more source