Results 31 to 40 of about 2,226,397 (316)
Role of amino acid transporters in amino acid sensing [PDF]
The American Journal of Clinical Nutrition, 2014 Amino acid (AA) transporters may act as sensors, as well as carriers, of tissue nutrient supplies. This review considers recent advances in our understanding of the AA-sensing functions of AA transporters in both epithelial and nonepithelial cells.
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COPASAAR--a database for proteomic analysis of single amino acid repeats. [PDF]
, 2005 Background Single amino acid repeats make up a significant proportion in all of the proteomes that have currently been determined. They have been shown to be functionally and medically significant, and are associated with cancers and neuro-degenerative ...
Depledge, D.P., Dalby, A.R.
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AnimalsTwo 35-day trials were conducted to determine the arginine (Arg) requirement of broiler chickens and the Arg and energy-sparing effects of guanidinoacetic acid (GAA). In experiment 1, a low-Arg diet (basal diet) was supplemented with increasing levels (0.
Adriaan Verhelle, Behnam Saremi
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Amino acid neurotransmitters in the CNS
FEBS Letters, 1986 D‐Aspartate exchange, defined as amino acid‐stimulated D‐[3H]aspartate efflux, was investigated in a preparation of rat brain synaptosomes. The efflux of radiolabelled D‐aspartate was found to be enhanced by micromolar concentrations of externally added D‐ and L‐aspartate, L‐glutamate, L‐cysteate.and L‐cysteinesulphinate.
Erecińska, Maria, Troeger, Melody B.
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The catalytic subunit of the system L1 amino acid transporter (Slc7a5) facilitates nutrient signalling in mouse skeletal muscle [PDF]
, 2014 The System L1-type amino acid transporter mediates transport of large neutral amino acids (LNAA) in many mammalian cell-types. LNAA such as leucine are required for full activation of the mTOR-S6K signalling pathway promoting protein synthesis and cell ...
Adel F M Ibrahim +31 more
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Research Progress of Amino Acid Metabolism PET Imaging in Tumor
Journal of Isotopes, 2015 Amino acid metabolism PET imaging plays a very important role in metabolism molecular imaging. Amino acid PET tracers include ［1-11C］amino acid, labeling α-C amino acid, labeling side-chain amino acid, and N-substituted labeling amino acid.
NIE Da-hong, TANG Gang-hua2
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Amino Acid Metabolism in Lupus
Frontiers in Immunology, 2021 T cell metabolism is central to cell proliferation, survival, differentiation, and aberrations have been linked to the pathophysiology of systemic autoimmune diseases.
Michihito Kono +2 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Amino acid uptake in Arabidopsis [PDF]
, 2008 Nitrogen (N) is essential for all living organisms and is considered to be the limiting factor for plant growth in many ecosystems. Although generally believed to rely on mineral N to fulfill their N needs, plants have also been found to access organic N
Svennerstam, Henrik
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
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