Results 81 to 90 of about 1,017,471 (305)
Expression of the hepatitis B surface antigen gene containing the preS2 region in Saccharomyces cerevisiae. [PDF]
, 1991 We constructed a plasmid, pBH103-ME5, in which the region encoding the 10 preS2 amino acid residues and the S domain of the hepatitis B surface antigen (HBsAg) were regulated by the promoter of the yeast repressible acid phosphatase gene.
Fujita, Hiyoyuki +4 more
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Amino Acid Composition of Dentin Protein.
Experimental Biology and Medicine, 1951 SummaryProtein prepared from the dentin removed from the crowns of non-carious, fully erupted, permanent, first and second human molars has been analyzed for lysine, arginine, histidine, hydroxyproline, phenylalanine, methionine, cystine, tryptophan, serine, threonine, glycine, alanine, and tyrosine.
F L, LOSEE, B A, NEIDIG, W C, HESS
openaire +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Application of Texture Analysis technique in formulation development of lyophilized orally disintegrating tablets containing mannitol, polyvinylpyrrolidone and amino acids [PDF]
, 2018 The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Orally disintegrating tablets (ODTs) attract a great attention as this easy swallowing dosage form often ...
Ermolina, I., Hackl, E. V.
core +2 more sources
Amino acid composition and protein dimension [PDF]
Protein Science, 2008 AbstractThere is indirect evidence that the amino acid composition of proteins depends on their dimension. The amino acid composition of a nonredundant set of about 550,000 proteins was determined and it was observed that, in the range of 50–200 residues, the percentage of occurrence of most of the residue types significantly depends on protein ...
openaire +2 more sources
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Amino acid composition of four tilapias [PDF]
, 2009 Adult Tilapia zillii, Sarotherodon galilaeus, Oreochromis aureus and O. niloticus were obtained from National Institute for Freshwater Fisheries Research hatchery. They were oven dried at 60degreesC for 50hours.
Ovie, S.O.
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Protein and DNA sequence determinants of thermophilic adaptation [PDF]
, 2005 Prokaryotes living at extreme environmental temperatures exhibit pronounced signatures in the amino acid composition of their proteins and nucleotide compositions of their genomes reflective of adaptation to their thermal environments.
Eugene I Shakhnovich +3 more
core +5 more sources